Radiation protective effect of green tea extract in mice irradiated with gamma rays

Abstract

Introduction: The aim of this study was to investigate the radiation protective effect of daily oral consumption (for one week/one month) and single oral dose of green tea extract against gamma irradiation in mice. Materials and Methods: This study was performed on 60 adult male Balb/c mice weighing 25 to 30 gr in 6 equal groups. These groups include control, only irradiated, daily consumption of 200 mg/kg of green tea extract for one week and without irradiation, irradiated group after consumption of 200 mg/kg extract for one week, irradiation after 200 mg/kg oral consumption of green tea extract for one month, and irradiation 2 hours after eating 800 mg/kg of green tea extract. Results: The results demonstrated that the oral consumption of green tea extract before irradiation significantly decreased MnPCE (51% decrease, P