Koomesh

Permanent URI for this collection

https://repository.brieflands.com/handle/123456789/60217

Browse

Now showing 1 - 20 of 1582

Assessment of the Risk Arising from a High Carbohydrate Diet in the Development of Cardiovascular Diseases in the Habitat of North of Iran (the PERSIAN Guilan Cohort Study)
(Brieflands, 2024-05-31) Masoumeh Moslemi; Marjan Mahdavi-Roshan; Farahnaz Joukar; Fariborz Mansour-Ghanaei
Background
The Necessity of Preserving Human Health from the Perspectives of Environmental Ethics and Medical Ethics
(Brieflands, 2024-05-31) Hesameddin Mehrfar; Ahmad Ghaderi
Environmental ethics as one of the branches of applied ethics deals with how human beings interact with the environment. Environmental pollutants endanger human health. On the other hand, the mission of medical ethics is to protect human health, and medical ethics principles include autonomy, beneficence, non-maleficence, and justice. Therefore, preserving human health is important in terms of environmental ethics and medical ethics, which is the goal of this article. Due to human activities, various pollutants have entered the oceans and seas, which have led to the change of life in these important aquatic ecosystems. Oil is one of the most important pollutants of the sea. Among the harmful effects of oil pollution, we can mention changes in human lifestyle, carcinogenesis, mutagenesis, prevention of light emission and oxygen penetration, and as a result the death of aquatic organisms. In terms of medical ethics, the country's health system is responsible for protecting community health. Apart from the technical and sociological approaches, investigating and solving environmental problems requires an ethical approach. Preservation of human health exists in the concepts of medical ethics and environmental ethics, so policymakers and decision-makers should prioritize the ethical evaluation of industrial projects that pollute marine environments to preserve the health of humans and marine organisms. Also, to prevent the destruction of the environment, all countries should try to achieve a global consensus.
The Latest Scientific Findings on Autophagy as a Double-Edged Sword in Progression and Treatment of Rheumatoid Arthritis
(Brieflands, 2024-05-31) Mobina Emadi; Mohammad Javad Mousavi; Hossein Khorramdelazad; Rasoul Baharlou; Maryam Masoumi; Jafar Karami
Autophagy is an important intracellular physiological mechanism that breaks down cytoplasmic organelles and components for energy supply. Autophagy also monitors cells by removing intracellular pathogens, damaged organelles, and abnormally accumulated proteins, which protect cells. Indeed, autophagy preserves and survives the cells by tracking the cytosol. It has been documented that there are relationships between autophagy and autoimmune diseases such as rheumatoid arthritis (RA). Autophagy is involved in various processes such as the development, survival, and proliferation of immune cells, thereby playing an important role in the pathogenesis of RA. In addition, autophagy is implicated in the process of protein citrullination, which is an important process in RA. It has been found that autophagy participates in the presentation of citrullinated peptides through MHC molecules to T lymphocytes, leading to immune response and chronic inflammation in RA. Furthermore, the body of evidence shows that autophagy enhances apoptosis resistance, and increases osteoclastogenesis (destruction of bone tissue), which ultimately leads to severe destruction of bone and cartilage. Due to the important role of autophagy in RA pathogenesis, we investigated the role of autophagy in important mechanisms involved in RA. This review article presents the autophagy involvement in mechanisms such as protein citrullination, osteoclastogenesis, survival of immune cells, apoptosis resistance, lymphocyte homeostasis, and its role in the clinical manifestations of RA.
Investigation of the Biochemical Changes of Sialidosis Disease and Its Relationship with NEU1 Gene in Two Khuzestanian Families by WES Method
(Brieflands, 2024-09-30) Nikoo Alsadat Jalali; Atousa Moradzadegan
Background and Objectives: Sialidosis (MIM 256550) is a rare, autosomal recessive inherited disorder caused by α-N-acetyl neuraminidase deficiency due to a mutation in the neuraminidase gene (NEU1) located at chromosomal locus 6p21.33. This genetic change leads to abnormal intracellular accumulation and urinary excretion of sialyloligosaccharides. The diagnostic method based on WES (Whole-Exome Sequencing) technology saves time and cost and provides the basis for more appropriate genetic counseling.
Study the Effect of Dry Needling of Leg Muscles on Ankle Joint Position Sense and Functional Disability in Patients with Chronic Ankle Sprain: A Randomized Clinical Trial
(Brieflands, 2024-03-31) Mohammad Amin Heydarian; Atefeh Aminianfar; Fatemeh Paknazar
Introduction
Bring your device in the hospital: a qualitative study
(Brieflands, 2023-12-31) Masoumeh Shahbazi; Mostafa AminiRarani; maryam jahanbakhsh; Shahram Tahmasebian
Introduction: The Bring Your Device (BYOD) approach has promoted the use of personal mobile devices to achieve organizational and occupational goals, but the use of this approach can bring various challenges and risks for health organizations. This research was conducted to identify the components of hospitals' readiness to use BYOD which can be used to develop appropriate policies and ultimately control related challenges.Materials and Methods: In this qualitative study, participants were selected using purposeful sampling with a snowball approach till reaching saturation point. For data gathering, semi-structured interviews were conducted with 15 experts in the BYOD field. Qualitative data were analyzed with the thematic analysis method and using MAXQDA Plus version 12 (Release 12.3.0, VERBI GmbH Berlin).Results: 6 main themes and 23 sub-themes were identified. The main themes include management principles, human resources, cost, technical infrastructure, legal considerations, and ethical considerations that play critical roles in hospitals' readiness for BYOD.Conclusion: Focusing on the issues identified in the form of formulating and implementing official programs as well as appropriate policies by the managers and stakeholders of the organizations can properly benefit from the advantages of BYOD and reduce the related challenges as much as possible.
A comparative study on effectiveness of acceptance and commitment therapy and logotherapy on symptoms of depression, anxiety and stress of women suffering relapsing remitting multiple sclerosis: A randomized controlled trial study
(Brieflands, 2018-12-31) Azim Azimi; Shahrokh Makvand; Mahmood Najafi; Parvin Rafieenia
Introduction: In recent years, psychological therapies increasingly used as complementary treatment along medication to help clinicians. The purpose of this study was to compare the effectiveness of two methods of group psychotherapy: Acceptance and commitment therapy (ACT) and logo therapy (LT) on the symptoms of anxiety, depression and stress in women with relapsing-remitting Multiple Sclerosis (RRMS). Materials and Methods: A sampling method was used to select 45 women from multiple sclerosis patients in Kermanshah (Iran). They were randomly assigned into two groups of experimental and one control group (n = 15 in each group). The first experimental group received 8 group sessions of ACT treatment. The second experimental group received 10 group sessions of LT as well, while the control group had just 8 simple group meeting with the therapist. All subjects completed Anxiety, Depression, and Stress Scales (DASS-42) before, after and three months after the application. Results: The mean of symptoms of anxiety, depression and stress in both experimental groups after intervention was significantly different with the mean of control group. However, no significant difference was observed between two experimental groups. Conclusion: Logo therapy and ACT are effective in decreasing the symptoms of depression, anxiety and stress in women with RRMS and could be recommended as adjunct therapies along with their medication.
Association between skin tag and diabetes mellitus
(Brieflands, 2012-06-30) Ramin Taheri; Batool Odi; Raheb Ghorbani
Introduction: Skin tags are small, benign, soft and pedunculated skin tumors. A possible association with impaired carbohydrate metabolism has been suggested in previous studies, but the results are not conclusive. This study was performed in order to determine association between skin tag and diabetes mellitus. Materials and Methods: This study was carried out on 80 patients with skin tags as a case group and 80 patients without skin tags as a control group that they were referred to Semnan dermatological clinics. Then fasting blood sugar (FBS) were checked out in both two groups. In addition, height and weight were measured in all patients and body mass index (BMI) calculated for each of the patient. Results: 43.8% and 55% of patients were respectively female in the case group and the control group. Age mean (± SD) was 44.3±16.6 and 37.3±18.9 years in the case and control group, respectively. BMI mean (±SD) index was 28.0±4.3kg/m2 in the patients with skin tag, whereas, it was 25.5±5.1 kg/m² in the patients without skin tag (P=0.001). Patients with skin tag had higher frequency of diabetes than patients in the control group (27.5% vs. 5%) and also the case group showed a higher frequency of pre diabetes than the control group (20% vs. 15%). The probability of presence of diabetes mellitus in the patients with skin tag was 6.82 times more than the patients in the control group (Odds ratio=6.82, 95% Confidence interval: 2.06-22.56, P=0.002). Conclusion: Our data suggest that there is an association between skin tag and diabetes mellitus. Therefore, screening of patients with skin tag is recommended for early diagnosis diabetes mellitus
Nuclear magnetic resonance -based metabolomics analysis of patients exposed to sulfur mustard in different stages using random forest method
(Brieflands, 2016-06-30) Bibi Fatemeh Nobakht Motlagh Ghoochani; Rasoul Aliannejad; Afsaneh Arefi Oskouie; fariba fattahi; Hossein Ali Sahakhah; Mostafa Rezaei-Tavirani
Introduction: Metabolomics is a powerful technique for determination of biomarkers. Here, we aimed to determine discriminatory metabolomic profiles in different stages of sulfur mustard-exposed patients (SMEPs). Materials and methods: Nuclear magnetic resonance spectroscopy was used to analyze serum samples from 17 SMEPs (normal group patients) and 17 SMEPs (severe group patients). Multivariate statistical analysis using random forest (RF) was performed on a ‘training set’ (70% of the total sample) in order to produce a discriminatory model classifying two groups of patients, and the model tested in the remaining subjects. Results: A classification model was derived using data from the training set with an area under the receiver operating curve (AUC) of 0.87. In the test set (the remaining 30% of subjects), the AUC was 0.8, thus RF model had good predictive power. We observed significant changes in lipid, amino acids and energy metabolism between two groups of patients. Conclusion: Nuclear magnetic resonance spectroscopy of serum successfully differentiates two groups of patients exposed to sulfur mustard. This technique has the potential to provide novel diagnostics and identify novel pathophysiological mechanisms, biomarkers and therapeutic targets
Anti-cancer effects of the combined treatment of trastuzumab and decoy oligodeoxynucleotides to target STAT3 transcription factor on SK-BR-3 breast cancer cell line
(Brieflands, 2023-02-28) Behrooz Johari; Roghayeh Ghorbani; Sara Heidari; Somayyeh Rashidi; Hamid Madanchi
Introduction: Breast cancer is the most common malignancy in the female population and is the leading cause of death. Surgery, chemotherapy, radiotherapy, and monoclonal antibody (trastuzumab) therapy are common and standard treatments for this cancer. However, there are significant limitations in the treatment of this disease by using regular methods. Given the role of transcription factors (TFs) in gene expression, differentiation therapy, and many cancer signaling pathways, in the present study, the effect of combined treatment of trastuzumab (Herceptin) and decoy oligodeoxynucleotides to target the STAT3 transcription factor on inhibition of HER2 positive SK-BR-3 cell line growth was investigated. Materials and Methods: At first, different concentrations of Trastuzumab were prepared from 0.1 to 100 μg/mL. In this way, the decoy and scramble oligodeoxynucleotides were designed and synthesized to target the STAT3 transcription factor. The transfection efficiency and combined effects of trastuzumab with decoy oligos on cell viability, apoptosis, and cell migration inhibition were evaluated. Results: The results showed that oligodeoxynucleotides labeled with Cy3 fluorophore (300 nM) enter the cells with high efficiency (81.7±6.9%). Combined treatment of cells by trastuzumab (10 μg/mL) along with decoy oligodeoxynucleotides (100 nM) led to a decrease in cell viability (58.86±2.71%), increased apoptosis (24.54±4.83%) and inhibited cell migration (45.95±4.21%). Conclusion: The results from this study showed the anticancer effects of combination therapy using trastuzumab with decoy oligodeoxynucleotides to target the STAT3 transcription factor in SK-BR-3 cells. Therefore, it seems that this strategy can be used as an adjunct to common treatments for breast cancer.
Effects of angiotensin II on expression of α3, αv and 3 integrin proteins in B16-F10 melanoma cells
(Brieflands, 2013-09-30) Newsha Esfandiary Yeganeh; Nazenik Galustanian; Aida Nasirzadeh Goljahi; Maryam Ghodrati; Roobina Boghozian; Elham Rasouli; Elham Abbasi; Orkideh Ghorban Dadrass; Maziar Akhavan
Introduction: Several reports indicated the role of angiotensin II antagonists in suppression of different tumvors. Some of the recent studies point to the increasing effect of angiotensin II on expression of important factors regarding to the tumor growth. Also the role of integrins in growth and metastasis of tumoral cells is very important but the role of angiotensin II in the expression of integrins is not clear yet. Materials and Methods: Melanoma tumors were induced in C57 mice using S.C. injections of B16-F10 cells. Losartan was I.P. injected to C57 mice. Also B16-F10 cells were cultured and incubated with angiotensin II with or without losartan for two hours and the expression of α3, αv and b3 integrins were studied using western blotting. Results: Our results indicate the suppressing role of losartan on tumor growth (day17, P=0.013 day18: P=0.0015). In addition angiotensin II increased significantly the expression of studied integrins in B16-F10 cultured cells (integrin αV: P=0.049 Integrin α3: P= 0.016 integrin β3: P= 0.037), and losartan completely abolished this effect. Conclusion: The role of angiotensin II in tumor growth may be because of reasons including its role in elevating the expression levels of α3, αv and 3 integrins. In animal model of melanoma, losartan suppressed the tumor growth through AT1 receptors inhibition. The present study indicates the importance of the drugs such as losartan besides the standard therapeutic approach for tumors
The attention needed for balance controlling in young patients with flatfoot
(Brieflands, 2016-10-31) Rozita Hedayati; Abdolhamid hajihasani; solale ramezanpour; Fatemeh Ehsani
Introduction: Regarding to the importance of foot in maintenance of balance, it seems that flat foot can affect complex postural and balance control. In this study dual-task paradigm has been used to investigate the amount of attention needed for balance controlling in patients with flat foot than subjects with normal foot arch. Materials and Methods: 30 participants (15 male ;15 female, mean ages 22/30±2/61 years) with flat foot and 30 participants (15 male ;15 female, mean ages 22.30 ± 1.70 years) with normal foot arch were placed in two groups. Static & Dynamic balance tests were performed by Biodex Balance System SD under condition of single leg stance, in two forms of open and closed eyes. Measured parameters were total, anterior-posterior and medial-lateral stability indices. Results: The within group comparison of single and dual tasks in control and flatfoot groups in static (open & closed eyes) and dynamic (open eyes) balance tests did not show any significant differences (P>.0.05). The within group comparison of single and dual tasks in two groups in dynamic balance condition with closed eyes showed significant differences (P
A comparative study on the anticonvulsive effects of the aqueous extrract ot the Rosmarinus officinalis plant with phenobarbitaln pentylentetrazol-induced seizures in mice
(Brieflands, 2002-03-31) Mohammad Taher Boroushaki; Farhad Malek; Abolghasem Baharloo
Introduction: The co nvulsive dis orders are among chro nic diseases, whic h usu ally need a long-term drug the rapy. Unfortunately, most of the drugs used clinically to treat disorde rs exer t many side effects. Therefore, searc h fo r finding new drugs is being carried o ut in many laboratories. The object of this research is a comparative study on the anticonvulsive effect of the aqueo us ext ract o f the plan t R osmarinu s offici na li s wit h p he no barbital in pentyleneterazol-induced seizures in mice. Materials and Methods: After acclimatizatio n, animals were randomly divided in different groups. Control group received normal saline (6 ml/kg), stan dard groups received (10, 20, 30 and 40 mg/kg ) phenobarbital and the test groups received aqueous plant extract (3, 6, 9 and 12 nil/kg). All injections were carried out as i.p. All animals were firstly exposed to pentylentetrazol (80 mg/kg, i.p). The onset of seizures, behaviora l changes, duration of the seizures and number of death were reco rded in all groups during the first 24 hours . Results: Results showed that all amounts of the plant extr acts delay the onse t of seizures but the most effective dose was 12 ml/kg , which was comparable to pheno ba rbital (30 mg/kg ). All amount of the extract, except 3 ml/kg, significantly reduced the dura tion of seizu res, compared to the contro l group. Number of death was 45, 0 and 10 percent in control, sta ndard and test group respect ively. Conclusion: Findings showed that 12 mllkg of the aqueous plant extract is able to reduce the o nse t o f se izu re s, dur at ion of se izu re s and number o f death a ft er 24 hours in pentylentetrazol-induced seizures.
Measurment and assessment of concentration of heavy metal (Hg, Cd, Pb) in canned tuna fish distributed in Mazandaran province of Iran in 2014-2015
(Brieflands, 2016-12-31) Mohammad Ali Zazouli; seied Mahmood mehdinia; Farzaneh Tabarinia; Davood Nasrollahpoor; tabarinia tabarinia
Introduction: Heavy metals are one of the pollutants which are found in minor amounts in natural water and high concentration in industry waste water. Heavy metals poisoning effects are increasing in marine organisms especially fishes due to disposal of industrial wastes to marine environment and their bio accumulation. The aim of this study is to determine of mercury, cadmium and lead levels in canned fish sold in Mazandaran province of Iran. Materials and Methods: This descriptive-cross sectional study was done on 12 types of canned tuna distributed, 3 numbers of each type and overall 36 sample. The concentration of 3 type heavy metals assessed with standard method by Atomic Absorption and then expressed based on µg/g of wet weight. The results were compared with WHO and Iran National Standard Organization. Results: The results show that, minimum and maximum of mercury level in 36 samples of canned tuna fish was 0.01 and 0.5 µg/g, cadmium 0.001 and 0.05 and lead 0.001 and 0.3 respectively. According to replicates experiments, the mean concentration of mercury in 12 such samples of canned tuna fish was from 0.106 to 0.31, cadmium from 0.006 to 0.022 and lead from 0.03 to 0.15µg/g. that there was a significant difference in samples(p
The prevalence of type 2 diabetes complications and their related factors in Semnan, Iran: a cross-sectional study
(Brieflands, 2023-06-30) Sayed Saeed Kassaeian; navid danai; Sadr Manouchehri Shahryar; Mohammad Hossein Taherian; Masoumeh Ebrahimi Tavani; Ali Heidari Roochi; Farid Gharibi
Introduction: Type 2 diabetes is a chronic disease and one of the major public health problems in societies due to its prevalence and complications. This study aims to assess the prevalence of type 2 diabetes complications and their related factors. Materials and Methods: This cross-sectional study included 400 diabetic patients (51% males vs. 49% females) in Semnan, Iran in 2023. The study tool was a researcher-made questionnaire whose content validity was confirmed by experts (CVR=0.90 and CVI=0.87). The descriptive results were calculated and reported as frequency (percentage) for qualitative variables and mean (standard deviation) for quantitative ones. Also, due to the qualitative nature of the variables, the statistical relationship between demographic and background variables with the prevalence of disease complications was evaluated using the chi-square test. Results: The mean age of participants was 51.93 years. According to the results, 19% of patients experienced type 2 diabetes complications, so that 8.5% had neuropathy (95% CI: ±2.73), 8% had retinopathy (95% CI: ±2.65), and 2.75% had nephropathy (95% CI: ±1.60). Among the demographic and background variables, the following items were significantly associated with the prevalence and severity of the complications: education level, employment status, nativity, urban or rural residency, type of basic health insurance, the time elapsed since diagnosis of the disease, the time interval between diagnosis of the disease and commencement of care, disease control status, and place of receiving care (P
Persian vowel formants an investigation and comparison between Persian children 7-9 years old and persian adult 18-22 years old
(Brieflands, 2008-03-31) Omid Mohammadi; Jamshid PorGharib
Introduction: Formant structure is one of the most important acoustical characteristics of sound. the relationship between first three formants is the main component of perceptual categorization by the listener. The quality and the kind of one vowel is related to its formant. Material and methods: The goal of this descriptive-analytical study was to assign and compare formant structure of Persian vowels between 50 Persian children 7-9 years old from two separate schools in Tehran (25 boys and 25 girls) and 50 adults aged between 18 and 22 from persian students and employees at the rehabilitation sciences faculty of Iran (25 men and 25 women). Six persian vowels (/i/,/e/,/æ/,/a/,/o/,/u/) were produced using simple sample. The first three formant of persian language vowels were obtained and compared between two groups of male adults and school boys and also female adults and school girls. Results: Fundamental frequency, first three formants of each vowel (F1, F2, F3), band frequency of each formant, and the intensity of each formant in each vowel were obtained and recorded by speech studio software and laryngograph device Conclusion: In all groups, /æ /vowel was the lowest height vowel and /i/ vowel is the highest high one. In addition, /i/ vowel was the high front vowel and /u/ vowel was the high back vowel one in all groups. The results of comparison of formant structure of Persian language vowels in two groups of male adults and school boys, and female adults and school girls suggested that all quantities of formant frequency of the Persian vowels in adults is lower than children, by what it says that male and female adults had lower formant frequencies in compare with boys and girls. These findings were similar to pervious same studies. The differences observed between children and adults are due to different vocal tract length and different size of resonator cavities.
A comparative study on the effects of aerobic walking and strength training programs on balance in patients with knee osteoarthritis
(Brieflands, 2022-02-28) Cyrus Taghizadeh Delkhoush; Elham Fatemi; Raheb Ghorbani
Introduction: Knee osteoarthritis is one of the most prevalent musculoskeletal disorder which can contribute to decrease in daily life balance.This study is carried out to compare the effects of aerobic walking and strength training programs on improving balance in women with osteoarthritis. Materials and Methods: Forty women with knee osteoarthritis were assigned randomly into two experimental (aerobic walking and strength training program) groups. Both groups exercised 3 days per week for 4 weeks. Static and dynamic overall stability index was evaluated three times by Biodex balance system and the average of each index was recorded. Results: Static balance score with open eye was significantly improved in the aerobic walking group (P=0.031) But this index did not change significantly in the strength training group. No significant difference discovered between two groups in term of other dynamic and static balance scores. Conclusion: The results showed that aerobic training was effective on the static balance with the open eyes but these interventions had no significant effect on dynamic balance and static balance with closed eyes. Another study with a larger sample size is recommended.
The Role of Cyclooxygenase-2 in Signaling Pathways Promoting Colorectal Cancer
(Brieflands, 2023-02-28) Abasalt Hosseinzadeh Colagar; Abdolvahab Moshtaghian; Tahereh Zahedi
Colorectal cancer is one of the most common cancers in the world. Various factors are involved in the development and progression of this disease. One of these agents is cyclooxygenase-2 (COX-2). COX-2 is a product of the PTGS2 gene and converts free arachidonic acid to prostaglandins. COX-2 is not naturally expressed in most normal cells. Noticeably, the increased expression of COX-2 has been observed in chronic inflammatory diseases and various cancers. COX-2 promotes colorectal cancer through various signaling pathways. COX-2 plays its role in colorectal cancer by induction of Bcl-2 expression, and β-catenin pathway activation, and leads to translocate of the NF-κB from the cytoplasm to the nucleus. NF-κB transcription factor plays an important role in physiological processes such as cell proliferation, cell death, and inflammation. Deregulation of NF-κB and its impact on the signaling pathway play a critical role in the development and progression of colorectal cancer. Another factor that plays a role in the development and progression of colorectal cancer is the β-catenin gene. Mutations in the β-catenin gene have been found in more than half of colorectal cancer patients. Bcl-2 is also known as an anti-apoptotic factor in all types of cancers. COX-2 controls all these pathways. Therefore, targeting COX-2 can be proposed as a therapeutic strategy for the treatment of colorectal cancer. The purpose of this review is to investigate the signaling pathways related to COX-2 in colorectal cancer
The effect of burn on cell mediated immunity
(Brieflands, 1999-12-31) parviz Kokhaei; Zahir MohammadHasan; Hossein Motieian; Fatemeh Pak
Introduction. In spite of new development in antibiotic production, infections are the main causes of death after burn injuries. This is due to skin destruction as the first defense barrier abd alteration in immune status of the burn patient. In this study, the effect of burn on cell medi ated immunity was studied. Material and Methods. Two groups were studied: experienta l group consist ing of lS patie nt ( 9 men and 9 woman ) with 20-60% burn of total body surface are and control gro up consisting 22 ( 11 men and 11 woman ) healthy persons . The average age of both group was 32 years and in each group subjects were equ al of boyh sexes. Immune sta tus was evaluated by T lymphocyte transformation test ( L.T.T) and HLA-DR as a cell activati on marker and also cell surface marker such as CD3, CD4 and CDS which are measured by monoclonal antibody and tlowcytometric analysis. Results. L.T.T of burned patients was significantly de crased in comparison of control grou p ( P< 0.0001). The tota l number of peri pheral bloob lymphocytes of burned patients was significantly lower than th at of control gro up (P
Effects of High-Intensity Interval and Mini-Trampoline Training with Calorie Restriction on Body Composition and Aerobic Capacity in Overweight and Obese women
(Brieflands, 2022-12-31) Elnaz Moghadam; Zohreh Eskandari; Mohammad Reza Shiri-Shahsavar; Masoud Mirmoezzi
Introduction: Weight gain and obesity are one of the most important health issues and one of the most severe public health problems. This study aimed to determine the effect of 10 weeks of High-Intensity Interval training (HIIT) and Mini-Trampoline training (MTT) with calorie restriction (CR) on body composition and aerobic capacity in overweight and obese women. Materials and Methods: Forty-eight overweight and obese women with a mean (age: 32.71±4.11 yrs, weight: 75.19±4.86 kg) participated in the present study based on the inclusion criteria and voluntarily. Subjects were randomly divided into four equal groups (12 subjects): Experimental group 1: MTT with CT, Experimental group 2: HIIT with CR, Experimental group 3: CR, and Control group: No restriction calories were divided. Body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHTR), skeletal muscle mass (SMM), and body fat percent (PBF) were analyzed using the Boca Model X1 body composition analyzer, and for aerobic capacity, the Cooper test was used. CR (deduction of 500 calories from the daily energy intake of individuals) was for 10 weeks. HIIT and MTT have performed three sessions per week and each session was one hour of high-intensity exercise. The control group was asked to continue their daily activities and maintain a normal diet. Results: A 10-week period of MTT with CR improved BMI (P=0.001), WHR (P=0.004), BF and PBF (P

Browse

Recent Submissions