Are Fetal Nuchal Translucency Thickness and Crown-rump Length Associated with Maternal Hematological and Biochemical Profile?

AuthorSaina Nassirien
AuthorSedigheh Hantoushzadehen
AuthorNasim Eshraghien
AuthorMarjan Ghaemien
AuthorZahra Panahien
OrcidSedigheh Hantoushzadeh [0000-0003-3779-9218]en
OrcidMarjan Ghaemi [0000-0003-2306-7112]en
Issued Date2023-12-31en
AbstractBackground: Nuchal translucency (NT) and crown-rump length (CRL) measurements are useful fetal screening tests. The extent to which maternal hematological and biochemical profiles may impact these markers has not been evaluated. This study is designed to address this issue. Methods: Data from the first-trimester screening for aneuploidy and maternal laboratory results, including maternal fasting blood sugar (FBS), thyroid stimulating hormone (TSH), hemoglobin, hematocrit, vitamin D3, and ferritin, were collected at 11 - 13 weeks of gestational age. The association between NT/CRL and maternal laboratory tests was analyzed and reported. Results: 258 women with a mean ± SD age of 32.6 ± 5.2 years participated in the study. NT and CRL values were not correlated with maternal laboratory variables. Otherwise, CRL was positively correlated with increasing maternal age, and NT was associated with increasing gestational age. Conclusions: The results of this study indicate that NT and CRL values at 11 - 13 weeks of gestation are independent of maternal hemoglobin, FBS, vitamin D3, and ferritin status.en
DOIhttps://doi.org/10.5812/fga-138371en
KeywordNuchal Translucencyen
KeywordCrown-Rump Lengthen
KeywordUltrasounden
KeywordScreeningen
KeywordThyroid-Stimulating Hormoneen
KeywordVitamin D3en
PublisherBrieflandsen
TitleAre Fetal Nuchal Translucency Thickness and Crown-rump Length Associated with Maternal Hematological and Biochemical Profile?en
TypeResearch Articleen

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