Antimicrobial Resistance Patterns of Bacterial and Fungal Isolates in COVID-19
Author | Rozita Khodashahi | en |
Author | Hamid Reza Naderi | en |
Author | Mosalreza Mohammadabadi | en |
Author | Reza Ataei | en |
Author | Mandana Khodashahi | en |
Author | Maliheh Dadgarmoghaddam | en |
Author | Sepideh Elyasi | en |
Orcid | Hamid Reza Naderi [0000-0002-3230-5576] | en |
Orcid | Mandana Khodashahi [0000-0003-1198-1783] | en |
Orcid | Maliheh Dadgarmoghaddam [0000-0002-4797-8714] | en |
Orcid | Sepideh Elyasi [0000-0001-9857-1175] | en |
Issued Date | 2022-02-28 | en |
Abstract | Background: The pattern of bacterial infection in coronavirus disease 2019 (COVID-19) patients differ worldwide. Objectives: This study aimed to determine the patterns of bacterial infections and the antibiotic resistance profile by VITEK 2 (bioMérieux, France) in the culture of blood samples from hospitalized patients with COVID-19. Methods: This retrospective descriptive cross-sectional was conducted on a total of 25 patients with critical COVID-19 admitted to Imam Reza Hospital in Mashhad, Iran, during the first three COVID-19 peaks (2019 - 2020). Results: Among Gram-positive bacteria, two strains isolated from Staphylococcus aureus were methicillin-resistant S. aureus at a concentration of > 2 μg/mL. Enterococcus was vancomycin-resistant Enterococcus at a concentration of higher than 4 μg/mL (the minimum inhibitory concentration [MIC] ≥ 32). Among Gram-negative bacteria, three strains of Acinetobacter baumannii complex were extensively drug-resistant. Conclusions: There is evidence of the remarkable increase of various antibiotics’ MIC during the COVID-19 pandemic, which highlights the impact of the use of steroids on the risk of developing antimicrobial resistance during the COVID-19 pandemic. | en |
DOI | https://doi.org/10.5812/archcid-121580 | en |
Keyword | COVID-19 | en |
Keyword | Carbapenemase-Producing <i>Enterobacteriaceae</i> | en |
Publisher | Brieflands | en |
Title | Antimicrobial Resistance Patterns of Bacterial and Fungal Isolates in COVID-19 | en |
Type | Research Article | en |
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