Antimicrobial Resistance Patterns of Bacterial and Fungal Isolates in COVID-19

AuthorRozita Khodashahien
AuthorHamid Reza Naderien
AuthorMosalreza Mohammadabadien
AuthorReza Ataeien
AuthorMandana Khodashahien
AuthorMaliheh Dadgarmoghaddamen
AuthorSepideh Elyasien
OrcidHamid Reza Naderi [0000-0002-3230-5576]en
OrcidMandana Khodashahi [0000-0003-1198-1783]en
OrcidMaliheh Dadgarmoghaddam [0000-0002-4797-8714]en
OrcidSepideh Elyasi [0000-0001-9857-1175]en
Issued Date2022-02-28en
AbstractBackground: The pattern of bacterial infection in coronavirus disease 2019 (COVID-19) patients differ worldwide. Objectives: This study aimed to determine the patterns of bacterial infections and the antibiotic resistance profile by VITEK 2 (bioMérieux, France) in the culture of blood samples from hospitalized patients with COVID-19. Methods: This retrospective descriptive cross-sectional was conducted on a total of 25 patients with critical COVID-19 admitted to Imam Reza Hospital in Mashhad, Iran, during the first three COVID-19 peaks (2019 - 2020). Results: Among Gram-positive bacteria, two strains isolated from Staphylococcus aureus were methicillin-resistant S. aureus at a concentration of > 2 μg/mL. Enterococcus was vancomycin-resistant Enterococcus at a concentration of higher than 4 μg/mL (the minimum inhibitory concentration [MIC] ≥ 32). Among Gram-negative bacteria, three strains of Acinetobacter baumannii complex were extensively drug-resistant. Conclusions: There is evidence of the remarkable increase of various antibiotics’ MIC during the COVID-19 pandemic, which highlights the impact of the use of steroids on the risk of developing antimicrobial resistance during the COVID-19 pandemic.en
DOIhttps://doi.org/10.5812/archcid-121580en
KeywordCOVID-19en
KeywordCarbapenemase-Producing <i>Enterobacteriaceae</i>en
PublisherBrieflandsen
TitleAntimicrobial Resistance Patterns of Bacterial and Fungal Isolates in COVID-19en
TypeResearch Articleen

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
archcid-17-1-121580.pdf
Size:
198.58 KB
Format:
Adobe Portable Document Format
Description:
Article/s PDF