Effectiveness of Transdiagnostic Therapy Based on the Research Domain Criteria Framework Compared with Treatment as Usual and Transcranial Direct Current Stimulation for Adult Nonsuicidal Self-injury: A Randomized Controlled Trial

AuthorHossein Farrokhien
AuthorImanollah Bigdelien
AuthorAli Mashhadien
AuthorSeyed Ruhollah Hosseinien
OrcidHossein Farrokhi [0000-0002-7506-4960]en
OrcidImanollah Bigdeli [0000-0002-2116-3402]en
OrcidAli Mashhadi [0000-0002-6212-1372]en
OrcidSeyed Ruhollah Hosseini [0000-0001-7320-3501]en
Issued Date2023-12-31en
AbstractBackground: Nonsuicidal self-injury (NSSI) is a serious and prevalent problem among the adult population. Despite its significant issue in clinical settings, there is a lack of effective, evidence-based, and affordable treatment options for NSSI. Objectives: This study aimed to compare the efficacies of transdiagnostic therapy based on the Research Domain Criteria framework (TTB-RDoC) with treatment as usual (TAU) and transcranial direct current stimulation (tDCS) in the treatment of adult NSSI. Methods: A total of 68 males aged 18-30 years diagnosed with NSSI participated in this randomized controlled trial (RCT). Participants were randomly assigned to 3 groups: TTB-RDoC (n = 24), TAU (n = 22), and tDCS (n = 22). Nonsuicidal self-injury and transdiagnostic symptoms were assessed at baseline, post-treatment, and during a 12-month follow-up. Results: Both TAU and TTB-RDoC treatments resulted in significantly lower ratings across all measures compared to tDCS at post-treatment (all P values < 0.001). TAU and TTB-RDoC showed significantly greater reductions in NSSI (P = 0.001 [post-treatment]; P = 0.001 [follow-up]) compared to tDCS. Conclusions: TTB-RDoC treatment may be an effective strategy to improve long-term treatment outcomes in adult NSSI.en
DOIhttps://doi.org/10.5812/ijhrba-140120en
KeywordTransdiagnostic Therapyen
KeywordResearch Domain Criteriaen
KeywordTreatment as Usualen
KeywordTranscranial Direct Current Stimulationen
KeywordNonsuicidal Self-injuryen
PublisherBrieflandsen
TitleEffectiveness of Transdiagnostic Therapy Based on the Research Domain Criteria Framework Compared with Treatment as Usual and Transcranial Direct Current Stimulation for Adult Nonsuicidal Self-injury: A Randomized Controlled Trialen
TypeResearch Articleen

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