Effects of Pharmacist Intervention on the Utilization of Vancomycin in a Teaching Hospital
| Author | Maria Tavakoli-Ardakani | en |
| Author | Samaneh Ghassemi | en |
| Author | Afshin Mohammad Alizadeh | en |
| Author | Jamshid Salamzadeh | en |
| Author | Mojtaba Ghadiani | en |
| Author | Sara Ghassemi | en |
| Issued Date | 2015-10-31 | en |
| Abstract | In order to investigate the effect of pharmacist intervention on vancomycin use, this study was performed on all patients receiving vancomycin in the intensive care unit (ICU) and hematology-oncology ward of Taleghani Educational Hospital in Tehran, Iran. Vancomycin use was assessed during a pre- and post-intervention period in accordance with the Center of Disease Control and prevention (CDC) and Infectious Diseases Society of America (IDSA) guidelines. Following the intervention, there was a significant change in appropriate initiation of vancomycin (P = 0.009) and no significant improvement was observed in adequate dosage and the duration of therapy (P = 0.15 and P = 0.54 respectively); however, informing the physician resulted in discontinuation of the drug in 50% of inappropriate cases and vancomycin dosage was adjustedin 31% of cases. Temperature charts, culture results and pre-treatment CBC tests changed significantly (P = 0.02, P = 0.009 and P = 0.04 respectively). The rate of infusion related adverse drug reactions did not decrease significantly (P = 0.06); yet in 100% of patients, these reactions were resolved after notifying the nursing team. After pharmacist intervention,vancomycin use improved in some aspects. A significant improvement in appropriate initiation of therapy was observed; however, treatments continued despite negative cultures. It is necessary to optimize the use of vancomycin by performing more educational interventions. | en |
| DOI | https://doi.org/10.22037/ijpr.2015.1745 | en |
| Keyword | Pharmacist intervention | en |
| Keyword | Vancomycin | en |
| Keyword | Drug use evaluation | en |
| Keyword | Guidelines | en |
| Keyword | Antibiotic use | en |
| Publisher | Brieflands | en |
| Title | Effects of Pharmacist Intervention on the Utilization of Vancomycin in a Teaching Hospital | en |
| Type | Original Article | en |
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