Effect of Zinc Supplementation on Red Blood Cell Osmotic Fragility in hemodialysis Patients
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Abstract
Introduction:: Zinc deficiency may aggravate the effect of oxidative stress on RBC (Red Blood
Cell) of chronic uremia. In this study, there is an attempt to show the relationship between
the plasma zinc level and RBC osmotic fragility in hemodialysis patients. Patients and Methods:: Thirty five patients with low level of serum zinc (serum zinc level Results:: The mean serum zinc concentration among the participants increased and it was
statistically significant (p Discussion:: In this trial, oral zinc supplementation caused a significant rises in the plasma
zinc level after 6 weeks. Although Hb concentration was not changed during the trial the level
of osmotic fragility in red cells reduced significantly.