Study of XmnI polymorphism in 5´ region of the apoAI gene in Iranian hyperlipidemic subjects
| Author | Ahmadreza Bandegi | en |
| Author | Mohsen FirozRay | en |
| Author | AbdolVahab EhsaniZenoz | en |
| Author | MohammadReza AkbariEyedgahi | en |
| Author | AliAkbar Shabani | en |
| Author | Mojtaba Malek | en |
| Issued Date | 2004-12-31 | en |
| Abstract | Introduction: Several studies have demonstrated the relationship between polymorphisms in the ApoAI – CIII – AIV gene cluster and hyperlipidemia. This study was conducted to elucidate the association between polymorphism of ApoAI/XmnI and Iranian hyperlipidemic subjects. Materials and Methods: Total genomic DNA was prepared from seventy-six Iranian patient with primary hyperlipidemia and seventy-five normolipidemic subjects. The subjects in the control group were age- and sex-matched to the patients. Fragment of 392 bp for 5´ region of the apoAI gene (C-2500T) was amplified by polymerase chain reaction (PCR). Results: In the hyperlipidemic group, the genotype frequency of X1X1, X1X2, X2X2 were 0.63, 0.24, 0.13, respectively. In the control group those were 0.81, 0.11 and 0.08, respectivley. There was a significant difference (p | en |
| DOI | https://doi.org/ | en |
| Keyword | Polymorphism, XmnI, Hyperlipidemia, Apolipoprotein AI | en |
| Keyword | پلیمورفیسم، XmnI، هیپرلیپیدمی، آپولیپوپروتئین AI | en |
| Publisher | Brieflands | en |
| Title | Study of XmnI polymorphism in 5´ region of the apoAI gene in Iranian hyperlipidemic subjects | en |
| Type | Research Article | en |
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