Methylation of the GSTP1 gene promotor in colorectal cancer
| Author | Hamid Nomani | en |
| Author | Naghmeh Jalejo | en |
| Author | Bahram Yaghmaei | en |
| Author | Shahrokh Mohammadzadeh Ghobadlu | en |
| Author | AliAsghar Keshavarz | en |
| Issued Date | 2009-06-20 | en |
| Abstract | Background: Transcriptional silencing of tumor suppressor genes and tumor related genes like GSTP1 by methylation of promotor region CpG island is believed to be an important mechanism in tumorigenesis. The GSTP1 gene encodes the enzyme glutathione S-transferase Pi which defends the cells against oxidative damage and electrophilic carcinogens. | en |
| DOI | https://doi.org/ | en |
| Keyword | tumor related gene | en |
| Keyword | methylation | en |
| Keyword | CpG island | en |
| Keyword | glutathione S-transferase Pi | en |
| Keyword | colorectal cancer | en |
| Publisher | Brieflands | en |
| Title | Methylation of the GSTP1 gene promotor in colorectal cancer | en |
| Type | Research Article | en |
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