Treatment of Adult Patients with Acute Bacterial Rhinosinusitis: Official Practice Guideline of the Infectious Diseases and Tropical Medicine Research Center Advisory Committee
| Author | Soheil Roshanzamiri | en |
| Author | Amirali Jahanshahi | en |
| Author | Davood Yadegarinia | en |
| Author | Masoud Mardani | en |
| Author | Shervin Shokohi | en |
| Author | Amir Rajabi | en |
| Author | Nima Dehghan | en |
| Author | Pooya Vahedi | en |
| Author | Mohammad Hossein Ramezani | en |
| Author | Ilad Alavi Darazam | en |
| Orcid | Masoud Mardani [0000-0001-6082-072X] | en |
| Orcid | Shervin Shokohi [0000-0002-9611-2466] | en |
| Orcid | Ilad Alavi Darazam [0000-0002-4440-335X] | en |
| Issued Date | 2025-10-31 | en |
| Abstract | Context: Acute bacterial rhinosinusitis (ABRS) is a significant public health concern, affecting approximately 15% of the population annually, with a higher prevalence among women. The bacterial etiology primarily includes Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Due to regional variations in bacterial resistance patterns, there is a critical need for localized and evidence-based guidelines for better management in Iranian patients. Evidence Acquisition: A multidisciplinary team reviewed literature from Iranian and international databases published between January 1990 and 2024. Studies included epidemiological data on ABRS prevalence, bacterial resistance patterns, and clinical outcomes. Results: First-line empirical antibiotic therapy for uncomplicated ABRS in Iran includes amoxicillin-clavulanate (500 mg/125 mg three times daily or 875 mg/125 mg twice daily). In cases with high antibiotic resistance, high-dose amoxicillin-clavulanate (2000 mg/125 mg extended-release tablets twice daily) is preferred. Respiratory fluoroquinolones (levofloxacin or moxifloxacin) are recommended for penicillin-allergic patients, with alternative options for non-type I hypersensitivity cases. Conclusions: The guideline standardizes the antimicrobial approach to ABRS in Iran, considering local resistance patterns and clinical evidence. | en |
| DOI | https://doi.org/10.5812/archcid-162500 | en |
| Keyword | Sinusitis | en |
| Keyword | Rhinosinusitis | en |
| Keyword | Practice Guideline | en |
| Keyword | Iran | en |
| Publisher | Brieflands | en |
| Title | Treatment of Adult Patients with Acute Bacterial Rhinosinusitis: Official Practice Guideline of the Infectious Diseases and Tropical Medicine Research Center Advisory Committee | en |
| Type | Review Article | en |
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