The Association of <i>Helicobacter pylori</i> Infection with Endothelial Dysfunction in Pediatric Patients
| Author | Zahra Pourmoghaddas | en |
| Author | Narges Ansari | en |
| Author | Bahar Dehghan | en |
| Author | Fatemeh Famori | en |
| Author | Hosein Saneian | en |
| Orcid | Zahra Pourmoghaddas [0000-0002-5424-3919] | en |
| Issued Date | 2019-01-31 | en |
| Abstract | Objectives: The aim of this study was to evaluate endothelial dysfunction in pediatric patients with Helicobacter pylori infection. Methods: In a cross sectional study, 50 children between six and twelve years old were evaluated for Helicobacter pylori infection by a histopathologic specimen. C-reactive protein (CRP) and Interleukin -12 of all subjects was checked. Endothelial dysfunction was evaluated by echocardiography of brachial artery and through measuring flow mediated dilatation (FMD). Results: Mean of FMD level was significantly higher in children with H. pylori infection (P value: 0.04). Interlukin-12 (IL-12) was higher in children with H. pylori infection (P value: 0.04). Linear regression showed a positive association of Helicobacter pylori infection and endothelial dysfunction (beta = 0.3, P value = 0.08). Conclusions: Children with Helicobacter pylori infection have more endothelial dysfunction independent of IL-12. | en |
| DOI | https://doi.org/10.5812/pedinfect.82540 | en |
| Keyword | Child | en |
| Keyword | Endothelial Dysfunction | en |
| Keyword | <i>Helicobacter pylori</i> | en |
| Publisher | Brieflands | en |
| Title | The Association of <i>Helicobacter pylori</i> Infection with Endothelial Dysfunction in Pediatric Patients | en |
| Type | Research Article | en |
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