THE EFFECT OF STATIC ELECTROMAGNETIC FIELD ON CEPHALOTHIN-RESISTANT PSEUDOMONAS AEROGINOSA

Abstract

Pseudomonas aeroginosa is among the most common significant etiological agents of hospital-acquired diseases. Due to their multiple resistance against a variety of antibiotics, these bacteria pose serious threats especially in burned patients. Sometimes burned patients lose their lives due to multiple-resistant pseudomonal infections. In this project, efforts were made to resensitize cephalothin resistant Pseudomonas aeroginosa to this antibiotic by static electromagnetic field (SEMF). Sixty samples of cephalothin-resistant Pseudomonas aeroginosa, collected from the burn unit of Ahwaz Taleghani hospital, were subjected to 0.35 Tesla of SEMF with and without cephalothin. All the Pseudomonas aeroginosa strains became resensitized to 16µg/ml cephalothin. SEMF by itself did not exert any effect on this bacterium. If in-vivo experiments confirm this in-vitro results, SEMF could be used as a valuable tool for treatment of serious cutaneous pseudomonal infections in burned patients.