The Effect of Probiotics in Prevention of Necrotising Enterocolitis in Preterm Neonates in Comparison with Control Group
| Author | Elaheh Amini | en |
| Author | Hosein Dalili | en |
| Author | Nikoo Niknafs | en |
| Author | Mamak Shariat | en |
| Author | Maryam Nakhostin | en |
| Author | Saeid Jedari-Attari | en |
| Orcid | Mamak Shariat [0000-0002-7547-8004] | en |
| Issued Date | 2017-12-31 | en |
| Abstract | Background: Necrotizing enterocolitis (NEC) is a common dangerous gastrointestinal emergency in neonatology, especially in premature infants, which can cause serious problems. Objectives: This study was conducted to find out whether administration of probiotics could lead to prevention and/or treatment of NEC. Methods: 115 premature newborns weighting 750 - 1500 g or less than 32 weeks’ gestation were checked daily for NEC signs and weight gain and mean day of full feed achievement was recorded. Results: The incidence of NEC and C-reactive protein (CRP) rise showed a significant difference (P = 0.02) between the two (case and control) groups, but the difference regarding mean duration of oxygen therapy, TPN, full feeding achievement, and hospitalization was not significant. Conclusions: These results showed positive effects of probiotics on preventing and treating NEC, especially NEC grade 3 in ELBW and VLBW neonates. | en |
| DOI | https://doi.org/10.5812/ijp.7663 | en |
| Keyword | Probiotics | en |
| Keyword | NEC | en |
| Keyword | Premature Neonate | en |
| Publisher | Brieflands | en |
| Title | The Effect of Probiotics in Prevention of Necrotising Enterocolitis in Preterm Neonates in Comparison with Control Group | en |
| Type | Research Article | en |
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