A Comparative Study of the Management of Stage 2 hypertension by Combined therapy with Losartan, Amlodipine and Hydrochlorothiazide
| Author | Reza Jafarzadeh Esfehani | en |
| Author | Azadeh Mahmoodi Gharai | en |
| Author | Ali Jafarzadeh Esfehani | en |
| Author | Afsaneh Rezaie Kalat | en |
| Author | Faezeh Abbasi | en |
| Author | Majid Jalalyazdi | en |
| Issued Date | 2012-09-30 | en |
| Abstract | Background: The most effective and accurate treatment of hypertensive patients reduces cardiovascular events and improves the quality of life. Objective: This study compared the efficacy and safety of combined (combination therapy) with an angiotensin-receptor blocker (ARB) a calcium-channel blocker (CCB) (Losartan / Amloidipine 50/10mg) vs maximal combination doses of ARB with hydrochlorothiazide (Losartan /HCTZ 100/25 mg) and maximal combination doses of CCB with HCTZ (Amlodipine /HCTZ 10/25 mg) in the management of stage 2 hypertension. Methods: This randomized clinical trial (RTC) comprised 478 hypertensive patients with mean age 50.5±5.21 years, and took place between January 2010 and December 2011 in Vasei Hospital clinic in Sabzevar. Antihypertensive drugs were washed out after 5 days of discontinuation of drugs and the patients with mean blood pressure in sitting position ≥ 160 and | en |
| DOI | https://doi.org/ | en |
| URI | https://brieflands.com/journals/ircrj/articles/12801 | en |
| Keyword | Angiotensin Receptor Blocker | en |
| Keyword | Calcium Channel Blocker | en |
| Keyword | Hypertension | en |
| Publisher | Brieflands | en |
| Title | A Comparative Study of the Management of Stage 2 hypertension by Combined therapy with Losartan, Amlodipine and Hydrochlorothiazide | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- icrj-06-79.pdf
- Size:
- 908.51 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF