Effect of High-intensity Interval Training on Endothelial Function in Type 2 Diabetic Females
| Author | Shiva Abdi | en |
| Author | Vahid Tadibi | en |
| Author | Dariush Sheikholeslami-Vatani | en |
| Orcid | Vahid Tadibi [0000-0003-4560-5006] | en |
| Issued Date | 2021-12-31 | en |
| Abstract | Background: Flow-mediated dilation (FMD) is a noninvasive approach to examine endothelial function. Objectives: The purpose of this study was to investigate the effect of 12 weeks of high-intensity interval training (HIIT) on FMD and circulating levels of adropin and nitric oxide (NO) in females with type 2 diabetes. Methods: Thirty females with type 2 diabetes were randomly assigned into two equal groups of HIIT and control. The exercise program consisted of three sessions a week for 12 weeks. Each training session included 4 × 4-minute running intervals at 85 - 95% of maximal heart rate (HRmax) with 3-minute active recoveries at 50 - 60% of HRmax. Circulating levels of adropin, NO, glucose, HbA1c, insulin, HOMA-IR, as well as lipid profile, and body composition parameters were measured before and after the intervention. Results: A significant increase of FMD% was observed after the intervention in the HIIT group (P = 0.001). In addition, the circulation levels of adropin and NO enhanced as a result of HIIT (P = 0.012 and P < 0.001, respectively). There were also significant positive effects on the levels of lipid profile (except for HDL), FBS, and HbA1c; as well as on the insulin resistance and the body composition variables. There were no significant changes in the control group except an increase in the total cholesterol levels (P < 0.01). Conclusions: The results showed that 12 weeks of the HIIT program could improve the endothelial function, glucose-related indices, lipid profile, and body composition variables in females with type 2 diabetes. | en |
| DOI | https://doi.org/10.5812/asjsm.113566 | en |
| Keyword | Flow-Mediated Dilatation | en |
| Keyword | Adropin | en |
| Keyword | Nitric Oxide | en |
| Keyword | Diabetes Mellitus | en |
| Publisher | Brieflands | en |
| Title | Effect of High-intensity Interval Training on Endothelial Function in Type 2 Diabetic Females | en |
| Type | Research Article | en |
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