The Effect of Synchronized Forced Running with Chronic Stress on Short, Mid and Long- term Memory in Rats

AuthorMaryam Radahmadien
AuthorHojjatallah Alaeien
AuthorMohammad-Reza Sharifien
AuthorNasrin Hosseinien
Issued Date2013-03-01en
AbstractPurpose: Impairment of learning and memory processes has been demonstrated by many studies using different stressors. Other reports suggested that exercise has a powerful behavioral intervention to improve cognitive function and brain health. In this research, we investigated protective effects of treadmill running on chronic stress–induced memory deficit in rats. Methods: Fifty male Wistar rats were randomly divided into five groups (n=10) as follows: Control (Co), Sham (Sh), Stress (St), Exercise (Ex) and Stress and Exercise (St & Ex) groups. Chronic restraint stress was applied by 6h/day/21days and also treadmill running at a speed 20-21m/min for 1h/day/21days. Memory function was evaluated by the passive avoidance test in different intervals (1, 7 and 21 days) after foot shock. Results: Our results showed that: 1) Although exercise alone showed beneficial effects especially on short and mid-term memory (P Conclusion: The data correspond to the possibility that although treadmill running alone has helpful effects on learning and memory consolidation, but when it is synchronized with stress there is no significant benefit and protective effects in improvement of memory deficit induced by chronic stress. However, it is has a better effect than no training on memory deficit in stressed rats.en
DOIhttps://doi.org/10.5812/asjsm.34532en
KeywordMemoryen
KeywordPassive Avoidanceen
KeywordRunningen
KeywordStressen
PublisherBrieflandsen
TitleThe Effect of Synchronized Forced Running with Chronic Stress on Short, Mid and Long- term Memory in Ratsen
TypeResearch Articleen

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
56995-pdf.pdf
Size:
316.17 KB
Format:
Adobe Portable Document Format
Description:
Article/s PDF