Effects of <i>Rosmarinus Officinalis</i> Plant Extract on <i>Trichomonas Vaginalis</i> Parasites and <i>Candida albicans</i> under Laboratory Conditions: An Experimental Study
| Author | Saeide Saeidi | en |
| Author | Forogh Forgani | en |
| Author | Fereshteh Javadian | en |
| Author | Elham Javadian | en |
| Orcid | Saeide Saeidi [0000-0002-1091-6616] | en |
| Issued Date | 2019-07-31 | en |
| Abstract | Background: As we know metronidazole is a selective treatment for Trichomoniasis, however, it has many side effects, and, on the other hand, it is important to try finding natural alternative treatments. Objectives: The aim of this study was to investigate the effects of Rosmarinus officinalis plant extract on Trichomonas vaginalis parasites and Candida albicans under laboratory conditions. Methods: In this experimental study, Rosmarinus officinalis methanolic extracts were prepared. The anti-trichomoniasis effect was evaluated at concentrations of 0.1, 0.01, 0.001, 0.0004, 0.0002, and 0.0001 μg/mL in TYIS33 culture media and resulted data were analyzed by ANOVA. Results: The results of this study showed that in the concentration of 0.001 at 4 hours, the parasite was spherical and inactivated, while at concentrations of 0.0004, 0.001, 0.01, and 0.1 in 1 hour. The results of this study showed that Rosmarinus officinalis extract in concentration of 100 µg/mL has an inhibitory effect on Candida albicans, so that the highest inhibitory diameter was 18.3 ± 0.9 mm while two other strains exhibit resistance and no inhibitory zones. Conclusions: The results of this study showed that rosemary extract inhibits the growth of Trichomonas vaginalis and Candida albicans that can be used to treat infections. | en |
| DOI | https://doi.org/10.5812/gct.92867 | en |
| URI | https://brieflands.com/journals/gct/articles/92867 | en |
| Keyword | <i>Trichomonas Vaginalis</i> | en |
| Keyword | <i>Candida albicans</i> | en |
| Keyword | <i>Rosemary</i> | en |
| Keyword | Laboratory Conditions | en |
| Publisher | Brieflands | en |
| Title | Effects of <i>Rosmarinus Officinalis</i> Plant Extract on <i>Trichomonas Vaginalis</i> Parasites and <i>Candida albicans</i> under Laboratory Conditions: An Experimental Study | en |
| Type | Research Article | en |
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