3D Echocardiographic Normal Values of LV Volumes and EF in Iranian Populations

Abstract

Background: The structure and function of the left ventricle play pivotal roles in the diagnosis and management of cardiac diseases. Three-dimensional echocardiography-derived indices, including the left ventricular end-diastolic volume index (LVEDVI) and left ventricular end-systolic volume index (LVESVI), provide high accuracy in assessing cardiac function. However, reference values for these indices in the Iranian population are not well defined. Objectives: This study aimed to establish normal reference values for these indices in the Iranian population. Methods: This cross-sectional study was conducted in 72 healthy Iranian individuals (31 females and 41 males) aged 20 - 70 years. Participants without a history of cardiac or systemic disease were enrolled. Three-dimensional echocardiography was used to measure LVEDVI, LVESVI, ejection fraction (EF), left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), left ventricular mass (Mass), and body surface area (BSA). Data were analyzed using appropriate statistical methods. Results: The mean values of the measured indices were as follows: LVEDVI 60.90 ± 9.15 mL/m2, LVESVI 24.35 ± 5.41 mL/m2, EF 60.18 ± 5.49, LVEDD 4.71 ± 0.39 mm, and LVESD 3.12 ± 0.48 mm. Significant differences in some indices were observed between males and females (P < 0.05). Conclusions: Normal values of left ventricular structural and functional indices in the Iranian population did not differ significantly from global reference values. These findings may help develop diagnostic and therapeutic criteria tailored to the Iranian population. Further studies are recommended to evaluate these indices across different age groups and clinical conditions.