A Multi-diagnostic Screening Study of the Prevalence and Risk Factors of Echinococcosis in First-degree Family Members of Infected Patients Undergoing Surgical Treatment

Abstract

Background: Echinococcosis is a zoonotic infection caused by Echinococcus tapeworms. About 60% of patients remain asymptotic until severe stages. Early diagnosis of the infection in high-risk populations is of medical importance. Objectives: This study was designed to investigate the prevalence of echinococcosis among first-degree family members of the infected patients who underwent surgical treatment. Methods: A cross-sectional study was conducted to screen the first-degree family members of 96 patients who underwent surgical intervention at Imam Reza hospital, Mashhad, Iran, from September 2016 to March 2017. All family members were invited by phone calls to perform the serologic test, ultrasound examination, and chest X-ray test. Results: Forty-six (47.9%) patients participated in the study. A total of 114 family members performed the screening tests. Seven participants from five families (6.14%) were found to be infected in ultrasound examination (five females with a mean age of 36 years). There were no significant differences between the infected and non-infected groups concerning age (P = 0.921) and gender (P = 0.457). Conclusions: Screening the first-degree family members of patients with a confirmed echinococcosis infection results in the early diagnosis of infected patients, which is economically significant, especially in endemic areas.