The Effect of 12 Weeks of Theraband Resistance Training on IGF-1 and FGF-2 Levels and Their Relationships with Myokines on Bone Mineral Density of Osteosarcopenic Obese Women
Author | Negin Kazemipour | en |
Author | Mohammad Faramarzi | en |
Author | Ebrahim Banitalebi | en |
Orcid | Ebrahim Banitalebi [0000-0002-9943-9747] | en |
Issued Date | 2022-09-30 | en |
Abstract | Background: Muscle-induced insulin-like growth factor 1 (IGF-1) and fibroblast growth factor 2 (FGF-2) are important factors for muscle growth and maintenance. Objectives: This study aimed to investigate the effect of 12 weeks of Theraband resistance training on IGF-1 and FGF-2 levels and their relationships with myokines on bone mineral density (BMD) in older women with osteosarcopenic obesity. Methods: In this single-blind randomized clinical trial, 48 older women with osteosarcopenic obesity (mean age: 64.63 ± 3.68 years; fat percentage 45.4 ± 6.6%; BMI 33.1 ± 3.71 kg/m2; and T score of bone minerals density of femur and 1 - 4 lumbar spine -1.86 ± 1.42, based on the results of the DEXA test) were randomly divided into control (n = 22) and training (n = 26) groups. The training group performed 12 weeks of Theraband resistance training for all major muscle groups. Blood samples were collected 48 hours before and 12 weeks after the intervention. Results: After 12 weeks, a significant difference was observed in IGF-1 (P = 0.033) levels in the training group compared to the control group. Also, FGF-2 (P = 0.003) and IGF-1 (P = 0.013) levels increased significantly in the training group. However, there was no significant relationship between IGF-1 (P = 0.240) and FGF-2 (P = 0.806) levels and BMD. Conclusions: Theraband resistance training can be an appropriate training strategy to improve muscle mass in older adults with osteosarcopenic obesity by increasing IGF-1 and FGF-2 levels. | en |
DOI | https://doi.org/10.5812/jjcmb-130641 | en |
Keyword | Theraband Resistance Training | en |
Keyword | Obesity | en |
Keyword | Bone Mineral Density | en |
Publisher | Brieflands | en |
Title | The Effect of 12 Weeks of Theraband Resistance Training on IGF-1 and FGF-2 Levels and Their Relationships with Myokines on Bone Mineral Density of Osteosarcopenic Obese Women | en |
Type | Research Article | en |
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