Predictors of Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes

AuthorF Hosseinpanahen
AuthorM Ramboden
AuthorL Sadeghien
Issued Date2007-04-30en
AbstractNon-alcoholic fatty liver disease (NAFLD) is com-mon in patients with type 2 diabetes and its diagno-sis in clinics is based on ultrasonography. The aim of this study is to examine the role of some clinical and laboratory variables in predicting NAFLD diag-nosed by ultrasonography in patients with Type 2 diabetes. Material and Methods: The study was performed on 76 consecutive alcohol-negative and hepatitis B and C virus-negative patients, attending an endocrine clinic; all of them had undergone a complete clinical and biochemical work up, including demographic and anthropometric factors, lipid profiles, fasting plasma glucose, glycosilated hemoglobin (HbA1c), liver transaminases and alkaline phosphatase. Using ultrasonography, patients were divided into two groups, one with and the other without NAFLD. A logistic regression model was developed in stepwise manner to evaluate predictors of NAFLD. Results: Average age was 60±9 years. Forty-nine (64.5%) patients were female. Sixty-three patients (82.9%) had ultrasonography-diagnosed NAFLD. Average body mass index (BMI) was higher in NAFLD patients (29.4±4.4 kg/m2 vs. 24.8±3.8 kg/m2, Pen
DOIhttps://doi.org/en
KeywordNon-alcoholic fatty liver diseaseen
KeywordDiabetesen
KeywordSteatosisen
KeywordBody mass indexen
KeywordMetabolic syndromeen
PublisherBrieflandsen
TitlePredictors of Non-Alcoholic Fatty Liver Disease in Type 2 Diabetesen
TypeResearch Articleen

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