Risk Factors for Adverse Maternal and Neonatal Outcomes Within Two Hours After Delivery: A National Registry-Based Multinomial Logistic Regression Study in Iran
| Author | Reza Ali Akbari Khoei | en |
| Author | Sasan Marefat | en |
| Author | Kayvan Mirnia | en |
| Author | Sevda Riyahifar | en |
| Orcid | Reza Ali Akbari Khoei [0000-0002-6523-9640] | en |
| Orcid | Kayvan Mirnia [0000-0002-2974-6362] | en |
| Orcid | Sevda Riyahifar [0000-0001-5197-1761] | en |
| Issued Date | 2026-07-31 | en |
| Abstract | Background: Perinatal health indicators, such as early neonatal mortality within 2 hours after birth, stillbirth, maternal mortality, and obstetric complications, are important public health concerns. Identifying associated maternal and fetal factors may inform clinical risk assessment and healthcare planning. Objectives: This study examined associations between maternal and fetal characteristics and adverse perinatal outcomes using data from the Iranian national birth registry. Methods: This retrospective, registry-based study used a complete national extraction of 1,431,597 mother–neonate records from Iran in 2017. Maternal and neonatal variables included maternal age (< 18, 18 - 35, and > 35 years), neonatal sex, hypertensive disorders, a history of neonatal death, previous stillbirth, premature rupture of membranes (PROM), non-gestational diabetes mellitus, placenta accreta, and fetal arrhythmias. Multivariable multinomial logistic regression was used to estimate odds ratios (ORs) with 95% confidence intervals (CIs). Statistical significance was defined as P < 0.05. Results: Extremes of maternal age, hypertensive disorders, a history of adverse obstetric outcomes, PROM, non-gestational diabetes mellitus, placenta accreta, fetal arrhythmias, and male sex were associated with increased odds of adverse neonatal and maternal outcomes, including stillbirth, early neonatal mortality (≤ 2 h), and admission to the intensive care unit (ICU). Conclusions: The observed associations may help identify high-risk pregnancies; however, the observational design does not support causal inference. Further prospective studies are required. | en |
| DOI | https://doi.org/10.5812/jhrt-171614 | en |
| URI | https://brieflands.com/journals/jhrt/articles/171614 | en |
| Keyword | Neonate | en |
| Keyword | Fetus | en |
| Keyword | Perinatal Care | en |
| Keyword | Postpartum Period | en |
| Keyword | Iran | en |
| Publisher | Brieflands | en |
| Title | Risk Factors for Adverse Maternal and Neonatal Outcomes Within Two Hours After Delivery: A National Registry-Based Multinomial Logistic Regression Study in Iran | en |
| Type | Research Article | en |
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