Toxoplasma gondii Exposure and the Risk of Schizophrenia
| Author | Shahram Khademvatan | en |
| Author | Jasem Saki | en |
| Author | Niloufar Khajeddin | en |
| Author | Maryam Izadi-Mazidi | en |
| Author | Reza Beladi | en |
| Author | Behnaz Shafiee | en |
| Author | Zahra Salehi | en |
| Orcid | Jasem Saki [0000-0002-2966-9352] | en |
| Issued Date | 2014-11-01 | en |
| Abstract | Background: Schizophrenia is a major psychiatric disorder with a deeply destructive pathophysiology. There are evidences to indicate that infectious agents such as Toxoplasma gondii may play some roles in etiology of the disorder. Objectives: The current study aimed to determine the association between T. gondii exposure and the risk of schizophrenia. Materials and Methods: T. gondii IgG antibodies of 100 patients with schizophrenia as well as 200 healthy volunteers were assessed. The subjects also completed demographic questionnaires. Data was analyzed using the chi-square and Fisher exact tests. Results: The analyses confirmed the significant differences between healthy women and ones with schizophrenia (P = 0.001) as well as between males and females with schizophrenia (P = 0.009) in IgG positivity. Conclusions: The present study supported the contamination with T. gondii as a risk factor for schizophrenia just in women. | en |
| DOI | https://doi.org/10.5812/jjm.18789 | en |
| Keyword | <i>Toxoplasma gondii</i> | en |
| Keyword | Schizophrenia | en |
| Keyword | Toxoplasmosis | en |
| Keyword | Parasite | en |
| Keyword | Enzyme-Linked Immunosorbent Assay | en |
| Keyword | Iran | en |
| Publisher | Brieflands | en |
| Title | Toxoplasma gondii Exposure and the Risk of Schizophrenia | en |
| Type | Research Article | en |
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