Vitamin D Status in COVID-19 Patients Versus Non-COVID-19 Individuals and Its Association with the Severity of Infection
| Author | Yasamin Khosravani-Nezhad | en |
| Author | Mehrangiz Zangeneh | en |
| Author | Masoomeh Mesgarian | en |
| Author | Seyed Davar Siadat | en |
| Author | Mohammad Bagheri-Mansouri | en |
| Author | Zahra Vosoughi | en |
| Orcid | Yasamin Khosravani-Nezhad [0000-0001-6733-3908] | en |
| Orcid | Mehrangiz Zangeneh [0000-0003-1023-9528] | en |
| Orcid | Masoomeh Mesgarian [0000-0003-1023-9528] | en |
| Orcid | Seyed Davar Siadat [0000-0002-6892-5603] | en |
| Issued Date | 2022-07-31 | en |
| Abstract | Background: The recent severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has resulted in millions of confirmed cases of infection and death. Vitamin D modulates the adaptive and innate immune systems; therefore, vitamin D deficiency may be related to the severity of coronavirus disease 2019 (COVID-19). Methods: This study was performed on 122 COVID-19 patients and 122 non-COVID-19 individuals to determine the possible relationship between vitamin D deficiency and COVID-19 severity. Besides, the relationship between vitamin D status and the severity of disease was investigated in 49 patients without an underlying disease. The COVID-19 severity was defined based on O2 saturation, respiratory rate, and pulmonary involvement. Also, vitamin D status was defined as follows: Vitamin D deficiency (< 30 ng/mL) and vitamin D sufficiency (≥ 30 ng/mL). Results: The mean age of 122 COVID-19 patients, including 71 (58.2%) male patients and 51 (41.8%) women patients, was 59 ± 16 years in this study, while the mean age of the controls, including 61 male participants and 61 female participants, was 48 ± 13 years (P < 0.05). The mean vitamin D level was 34.14 ± 1 ng/mL in the patients and 32.94 ± 1 ng/mL in the controls (P = 0.872). However, there was no significant correlation in none of all the 122 patients and 49 patients without an underlying disease (P = 0.074, P = 0.261). Conclusions: Based on the present findings, the correlation between vitamin D status and COVID-19 severity was not significant neither in 122 patients, and nor in 49 patients without an underlying disease. | en |
| DOI | https://doi.org/10.5812/iji-124057 | en |
| URI | https://brieflands.com/journals/iji/articles/124057 | en |
| Keyword | COVID-19 | en |
| Keyword | Severity | en |
| Keyword | Vitamin D | en |
| Keyword | Deficiency | en |
| Publisher | Brieflands | en |
| Title | Vitamin D Status in COVID-19 Patients Versus Non-COVID-19 Individuals and Its Association with the Severity of Infection | en |
| Type | Research Article | en |
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