Lupus Erythematosus- Bullous Pemphigoid Overlap-Tale of a Rare Co-existence
| Author | Vasudha Abhijit Belgaumkar | en |
| Author | Snehal Pandurang Nile | en |
| Author | Shekhar Nana Pradhan | en |
| Author | Kiran Dange | en |
| Author | Rachana Raj | en |
| Author | Md Sarfaraz Ahmed Baag | en |
| Orcid | Vasudha Abhijit Belgaumkar [0000-0002-8951-8660] | en |
| Issued Date | 2025-03-31 | en |
| Abstract | Introduction: Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease, typically encountered as an isolated condition or, less frequently, in association with other autoimmune blistering diseases. Herein, we report a rare case of overlap between lupus erythematosus and bullous pemphigoid. Very few cases of this co-existence have been documented worldwide. Case Presentation: A young woman presented with intense itching, photosensitivity, and vesiculobullous lesions on the skin and oral mucous membranes, with histological features indicative of bullous pemphigoid (BP) and a positive serological test for lupus erythematosus (LE). There was marked improvement with the administration of dapsone and antimalarials. Conclusions: Vesiculobullous lesions in LE are a rare cutaneous manifestation of cutaneous and/or systemic LE, presenting with variable and atypical features that can lead to diagnostic difficulty and delay. The diagnosis and management of LE-associated vesiculobullous diseases remain challenging due to the similarities in clinical and immunohistopathological features. | en |
| DOI | https://doi.org/10.5812/jssc-160130 | en |
| URI | https://brieflands.com/journals/jssc/articles/160130 | en |
| Keyword | Autoimmune Diseases | en |
| Keyword | Lupus Erythematosus | en |
| Keyword | Bullous Pemphigoid | en |
| Keyword | Overlap Syndrome | en |
| Keyword | Subepidermal Blister | en |
| Publisher | Brieflands | en |
| Title | Lupus Erythematosus- Bullous Pemphigoid Overlap-Tale of a Rare Co-existence | en |
| Type | Case Report | en |
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