Analgesic Efficacy of Interpleurally Administered Morphine and Fentanyl After Posterolateral Thoracotomy
| Author | Shideh Dabir | en |
| Author | Tahereh Parsa | en |
| Author | Badiozaman Radpay | en |
| Author | Saviz Pozhhan | en |
| Author | Ali Akbar Khadem Maboudi | en |
| Author | Mohammad Abbasi-nazari | en |
| Author | Jamshid Salamzadeh | en |
| Issued Date | 2007-01-31 | en |
| Abstract | Pain control is a major concern in post-thoracotomy patients. The current prospective randomized double-blind study was designed to evaluate the analgesic effects of morphine and fentanyl given interpleurally after posterolateral thoracotomy. Thirty patients undergoing elective posterolateral thoracotomy in a teaching hospital in Tehran were divided into 3 groups with equal number of patients. Patients in group IPM, IPF1 and IPF2 received 0.1 mg/kg morphine sulfate, 5 µg/kg fentanyl and 2.5 µg/kg fentanyl in a total volume of 40 ml injected via an intrapleural catheter placed in the pleural space before the closure of chest. Subsequent doses of interpleural injections were administered at 4 and 8 h after operation. The intensity of pain was evaluated at rest and with coughing just before each interpleural injection and 30 min afterwards using a 10 point visual analogue scale (VAS). If patients needed additional analgesia, indomethacin suppository and intravenous morphine were given during the 20-h postoperative study period. In all of the 3 study groups VAS scores were significantly reduced 30 min after interpleural administration of the study solutions (p | en |
| DOI | https://doi.org/10.22037/ijpr.2010.699 | en |
| Keyword | Fentanyl | en |
| Keyword | morphine | en |
| Keyword | Interpleural analgesia | en |
| Keyword | Pain | en |
| Keyword | Thoracotomy | en |
| Publisher | Brieflands | en |
| Title | Analgesic Efficacy of Interpleurally Administered Morphine and Fentanyl After Posterolateral Thoracotomy | en |
| Type | Research Article | en |