Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue
Author | Asghar Maziar | en |
Author | Daryoush Shahbazi-Gahrouei | en |
Author | Mohammad Bagher Tavakoli | en |
Author | Vahid Changizi | en |
Orcid | Vahid Changizi [0000-0003-2015-1642] | en |
Issued Date | 2015-12-28 | en |
Abstract | Background:: Using hair samples to analyze the trace element concentrations is of interest among many researchers. X-ray fluorescence (XRF) and X-ray diffraction (XRD) are the most common methods in studying the structure and concentration of elements of tissues and also crystalline materials, using low energy X-ray. Objectives:: In the present study, the detection ability of Wave Length X-ray Fluorescence (WLXRF) of breast cancer at early stages was evaluated and the results were compared with other routine modalities such as mammography. Materials and Methods:: Hair samples of 54 women (including 27 healthy and 27 patients) with average age of 52.03 ± 11.44 years were analyzed. All the sample donors were Iranian women. For the measurements Wave Length X-ray Fluorescence (WLXRF) method was used. Results:: Trace elements in healthy individuals were higher than those in cancer patients. In addition, sensitivity of the used method (WLXRF) was 96% compared to mammography (77%) as a gold standard for breast cancer detection. Conclusions:: Trace elements in healthy individuals were higher than cancer patients and it seems that WLXRF may be used as a safe, low cost and reliable method with sensitivity higher than those of the other two relevant methods, XRD and mammography. | en |
DOI | https://doi.org/10.17795/ijcp-3983 | en |
Keyword | Wave Length X-Ray Fluorescence (WLXRF) | en |
Keyword | Breast Tissue | en |
Keyword | Human Hair | en |
Keyword | Non-Invasive | en |
Publisher | Brieflands | en |
Title | Non Invasive XRF Analysis of Human Hair for Health State Determination of Breast Tissue | en |
Type | Research Article | en |
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