Combined Application of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Inhibitors Suppresses Cell Growth and Promotes Apoptosis in Human Lung Cancer Cell Lines
Author | Marzieh Badinloo | en |
Author | Saeed Esmaeili Mahani | en |
Issued Date | 2016-10-31 | en |
Abstract | PI3K/Akt/mTOR would be an important intracellular signal pathway which has found to be over-activated in neoplasia. Here, the combination effect of LY294002 (PI3K inhibitor) and rapamycine (mTOR inhibitor) has evaluated in different human lung cancer cell lines. | en |
DOI | https://doi.org/10.17795/ijcp-3433 | en |
Keyword | Lung Cancer | en |
Keyword | PI3K | en |
Keyword | mTOR | en |
Keyword | LY294002 | en |
Keyword | Rapamycin | en |
Keyword | Apoptosis | en |
Publisher | Brieflands | en |
Title | Combined Application of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Inhibitors Suppresses Cell Growth and Promotes Apoptosis in Human Lung Cancer Cell Lines | en |
Type | Research Article | en |
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