Central Neck Ultrasound: A Single-Center Experience of Its Diagnostic Accuracy After Thyroidectomy in Patients with Thyroid Cancer
| Author | Vida Ghanbari | en |
| Author | Shabnam Niroumand | en |
| Author | Elham Rahmanipour | en |
| Author | Seyed Ali Alamdaran | en |
| Orcid | Vida Ghanbari [0009-0009-2222-0550] | en |
| Orcid | Shabnam Niroumand [0000-0002-6479-1636] | en |
| Orcid | Elham Rahmanipour [0000-0001-8454-458X] | en |
| Orcid | Seyed Ali Alamdaran [0000-0002-5966-2856] | en |
| Issued Date | 2024-12-31 | en |
| Abstract | Background: Ultrasonography (US) plays a crucial role in managing recurrent and persistent tumors in thyroid cancer, the most common endocrine malignancy, affecting approximately half a million people worldwide annually. Objectives: This study investigates the use of local US criteria to differentiate between post-operative changes (such as seroma, granulation tissue, and surgical material), residual normal thyroid tissue, tumor remnants, metastatic adenopathy, and nonspecific lesions after thyroidectomy in patients with thyroid cancer. Methods: A total of 177 thyroid cancer patients (76.3% female) were referred to the US and followed up for a final histopathological diagnosis. US results were compared with needle biopsy findings. Results: Histopathology confirmed 95.8% (113/118) of the US-identified lesions as malignant and 78.6% (44/56) as benign. In total, 125 lesions were malignant, while 49 were benign. The US had a sensitivity of 90.4%, specificity of 89.8%, diagnostic accuracy of 90.23%, positive predictive value (PPV) of 95.76%, and negative predictive value (NPV) of 78.57%. The positive and negative likelihood ratios were 8.9 and 0.11, respectively. Vascular patterns had the highest sensitivity, specificity, and accuracy among the parameters studied, but shape and echogenicity were unsatisfactory. Conclusions: Our results demonstrated that the US has around 90% sensitivity and specificity in identifying malignancy in postoperative thyroid cancer patients. These findings suggest that neck US is an effective technique for diagnosing thyroid bed lesions. | en |
| DOI | https://doi.org/10.5812/ijcm-147670 | en |
| Keyword | Thyroid Cancer | en |
| Keyword | Ultrasound | en |
| Keyword | Recurrence | en |
| Keyword | Adenopathy | en |
| Keyword | Lymph Nodes | en |
| Publisher | Brieflands | en |
| Title | Central Neck Ultrasound: A Single-Center Experience of Its Diagnostic Accuracy After Thyroidectomy in Patients with Thyroid Cancer | en |
| Type | Research Article | en |