The role of connective tissue genomics in ascending aortic dissection: A case of Marfan syndrome
| Author | Firoozeh Madadi | en |
| Author | manouchehr hekmat | en |
| Author | Zahra Ansari Aval | en |
| Author | Abdolhamid Bagheri | en |
| Author | Kamal Fani | en |
| Author | Mohammad Hosein Ghanbarpour | en |
| Author | maryam hamidzad | en |
| Author | Mehrubon Murodov | en |
| Author | Ali Dabbagh | en |
| Orcid | Firoozeh Madadi [0000-0001-9293-1440] | en |
| Orcid | Zahra Ansari Aval [0000-0001-5019-2563] | en |
| Orcid | Kamal Fani [0000-0002-7921-257X] | en |
| Orcid | Ali Dabbagh [0000-0003-4344-8131] | en |
| Issued Date | 2019-09-30 | en |
| Abstract | Background: Aortic dissection is a rare yet life threating condition with some already discovered risk factors namely hypertension, connective tissue disorders such as Marfan syndrome (MFS), cocaine abuse and cigarette smoking.Case report: In this article we would like to present a case of MFS who presented with severe chest pain and undergone Bentall surgery due to aortic dissection and aneurysm.Conclusion: Although many risk factors and preventive measures are already investigated, there is no definite method to avoid its occurrence in genetically predisposed patients such as MFS. Patient-specific models utilizing embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) may offer some advantages. | en |
| DOI | https://doi.org/10.22037/jcma.v4i3.28189 | en |
| URI | https://brieflands.com/journals/jcma/articles/149588 | en |
| Keyword | Marfan syndrome - Aortic dissection - iPSC - cocaine | en |
| Publisher | Brieflands | en |
| Title | The role of connective tissue genomics in ascending aortic dissection: A case of Marfan syndrome | en |
| Type | Brief Report | en |
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