Rho GDP Protein Expression Change and Investigation of ItsEffect on GDP/GTP Cycle in Human Brain Oligodendroglioma
| Author | Solmaz Khaghani Razi Abad | en |
| Author | Mehdi Pooladi | en |
| Author | Mehrdad Hashemi | en |
| Author | Afshin Moradi | en |
| Author | Sara Sobhi | en |
| Author | Alireza Zali | en |
| Author | Masoumea Mousavi | en |
| Author | Hakimeh Zali | en |
| Author | Mona Zamanian Azodi | en |
| Author | Azadeh Rakhshan | en |
| Author | Reza Vafaee | en |
| Author | Mostafa Rezaei Tavirani | en |
| Issued Date | 2013-12-31 | en |
| Abstract | Background: Oligodendrogliomas are sub-types of Gliomas with an enriched net of branching capillary. A vast amount of Oligodendroglial (approximately 60-90%) demonstrates a loss of 1p and 19q chromosomes, and their response to radio and chemotherapy treatments are considerably more favorable and less aggressive. Rho GDP inhibitor is a protein which controls the activity and distribution of GTPase in cells. In cancer cells with 1pLOH deletion, Rho GDP inhibitor protein can be anti-apoptotic. Here understanding of molecular diagnosis of Oligodendroglioma tumors is investigated via proteomic tools. | en |
| DOI | https://doi.org/ | en |
| URI | https://brieflands.com/journals/ijcm/articles/80454 | en |
| Keyword | Rho GDP | en |
| Keyword | Oligodendroglioma | en |
| Keyword | Two-Dimensional electrophoresis | en |
| Keyword | Proteomics | en |
| Keyword | Brain tumors | en |
| Publisher | Brieflands | en |
| Title | Rho GDP Protein Expression Change and Investigation of ItsEffect on GDP/GTP Cycle in Human Brain Oligodendroglioma | en |
| Type | Research Article | en |
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