The effect of sodium salicylate injection on spatial learning and memory of rat

Abstract

Background: Cyclooxygenase (COX) enzyme known as a regulatory factor in synaptic plasticity. It has been reported that synaptic plasticity is one of the mechanisms involved in learning and memory processes. In the current study peripheral injection's effects of sodium salicylate (as a non selective COX inhibitor) on spatial learning and memory have been investigated.