Treatment of Colchicine-Resistant Familial Mediterranean Fever With Anakinra
| Author | Vadood Javadi Parvaneh | en |
| Author | Reza Shiari | en |
| Orcid | Reza Shiari [0000-0001-6906-1053] | en |
| Issued Date | 2015-07-01 | en |
| Abstract | Introduction: Familial Mediterranean Fever (FMF) is an auto-inflammatory disease presenting with periodic fever and various clinical manifestations. Almost 10% of the patients with FMF do not respond to colchicine therapy. Case Presentation: Herein was reported a colchicine non-responsive patient with accurate diagnosis and early treatment of FMF. She had presented with recurrent and persistent acute abdominal pain attacks and several abdominal surgeries. Addition of recombinant interleukin-1 receptor antagonist (Anakinra) to colchicine was effective to decrease the number and severity of abdominal pain in the patient. Conclusions: This case showed the effect of additional Anakinra on children with FMF who were colchicine resistant. | en |
| DOI | https://doi.org/10.5812/pedinfect.21664v2 | en |
| Keyword | Familial Mediterranean Fever | en |
| Keyword | Colchicine | en |
| Keyword | Interleukin-1 Receptor Antagonist Protein | en |
| Publisher | Brieflands | en |
| Title | Treatment of Colchicine-Resistant Familial Mediterranean Fever With Anakinra | en |
| Type | Case Report | en |
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