Gastric Cancer: Correlation of Histologic Type with Commonly Used Prognostic Variables
| Author | Afsoon Taghavi | en |
| Author | Atieh Khorsand | en |
| Author | Malihe Saberafsharian | en |
| Author | Reza Sahabi | en |
| Author | Mozhdeh Beiraghdar | en |
| Author | Mitra Hosseinpour | en |
| Author | Sara Zahedifard | en |
| Author | Hadi Hajizadeh Fallah | en |
| Author | Reza Maghsoodi | en |
| Author | Sareh Salarinejad | en |
| Author | Parto Nasri | en |
| Author | Hamid Reza Eftekhari | en |
| Author | Zahra Sadeghzadeh | en |
| Author | Masoumeh Hosseini | en |
| Author | Arsham Moradi | en |
| Author | Leila Bahari Khasraghi | en |
| Orcid | Malihe Saberafsharian [0000-0002-0115-8016] | en |
| Orcid | Sara Zahedifard [0000-0002-2935-5951] | en |
| Issued Date | 2023-12-31 | en |
| Abstract | Background: Gastric cancer is one of the most common cancers among Iranian men and women. Objectives: The aim here was to investigate different histopathologic types and features of this cancer in association with selected prognostic variables. Methods: A retrospective cross-sectional study was performed to reevaluate the pathologic samples of 100 cases of gastric cancer referred to Shohadaye Tajrish Hospital, Tehran, Iran from 2017 to 2022. Results: We evaluated 100 cases of gastric cancer in this study. They had a mean age of 62.4 ± 13.44 years old (range 28 - 84 years) and were mostly men (n = 66, 66 %). On histopathologic evaluation, tubular carcinoma was the most common type (n = 45, 45%). We found a statistically significant correlation between the histologic type and perineural invasion (P-value = 0.024), lymphovascular invasion (P-value < 0.001), tumoral involvement of surgical margin (P-value = 0.012 ), infiltration depth of the primary tumor (pT) (P-value = 0.049) , number of metastatic lymph nodes (pN) (P-value = < 0.001) , tumor location in the antrum (P-value=0.033) and body (P-value = 0.013) , and tumor size (P-value = 0.002 and P-value = 0.031 in small and large size groups respectively). Conclusions: According to the findings, histologic type of gastric cancer correlates with perineural invasion, lymphovascular invasion, tumoral involvement of the surgical margin, pT, pN, and tumor location and size. | en |
| DOI | https://doi.org/10.5812/ijcm-134832 | en |
| Keyword | Gastric Cancer | en |
| Keyword | Perineural Invasion | en |
| Keyword | Lymphovascular Invasion | en |
| Keyword | Surgical Margin | en |
| Keyword | WHO Classification System | en |
| Keyword | TNM Staging System | en |
| Publisher | Brieflands | en |
| Title | Gastric Cancer: Correlation of Histologic Type with Commonly Used Prognostic Variables | en |
| Type | Research Article | en |
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