Serological Markers of Blood Borne Viruses among Persons with Combined Factor V and VIII Deficiency
| Author | Hassan Mansouritorghabeh | en |
| Author | Reza Farid Hosseini | en |
| Author | Aliakbar Pourfathollah | en |
| Author | Azizollah Behjati | en |
| Issued Date | 2008-09-30 | en |
| Abstract | Background and Aims: Combined factor V and VIII deficiency (CF5F8D) is a rare hemorrhagic disorder. Treatment of patients with blood products has been associated with infections with blood-borne viruses. Due to absence of any survey on status of blood borne viruses in individuals with CF5F8D, we tried to address this question. Methods: Among 25 known cases, 24 individuals were assessed for hepatitis B and C viruses (HBV & HCV), human T lymphotropic virus type one (HTLV-I) and human immunodeficiency virus type1/2 (HIV1/2) using enzyme linked immunosorbent assay method. Results: In the group under survey, 2 cases (8.3%) were positive for anti-HCV. There was no infection with HBV, HTLV-I and HIV. Conclusions: Hepatitis C is a major health problem in CF5F8D, as in hemophiliacs, and may need more attention from manufacturers of blood products and more careful pre-transfusion screening of blood products for anti-HCV. | en |
| DOI | https://doi.org/ | en |
| Keyword | CF5F8D | en |
| Keyword | Hemophilia | en |
| Keyword | HCV | en |
| Keyword | HBV | en |
| Keyword | HIV1/2 | en |
| Keyword | HTLV-I | en |
| Publisher | Brieflands | en |
| Title | Serological Markers of Blood Borne Viruses among Persons with Combined Factor V and VIII Deficiency | en |
| Type | Brief Report | en |
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