A Case of Progressive Rhino-Orbital Mucormycosis Involving the Brain Via Direct Extension, Retrograde Perineural Spreading and Middle Cerebral Artery Vasculopathy

AuthorBahaadin Siroosen
AuthorZahra Sharify Bahramen
AuthorOmid Ghaemien
AuthorSeyyed Mahdi Zia Ziabarien
AuthorMojtaba Hedayat Yaghoobien
Issued Date2014-06-30en
AbstractIntroduction: Rhino-orbito-cerebral mucormycosis is a progressive angioinvasive fungal disorder which almost always complicates immunocompromised patients. Case presentation: We described a case of fulminant rhino-orbito-cerebral mucormycosis in a 65-year-old woman, who presented with progressive neurological deficits due to involvement of orbital apex and the central nervous system by local invasion of the left inferior frontal lobe, retrograde perineural spreading to the brain stem and middle cerebral arteries thrombosis. Discussion: Early diagnosis is mandatory in managing of this life-threatening disorder. Urgent surgical debridement associated with antifungal agents (amphotericin with posaconazole) is the mainstay of treatment.en
DOIhttps://doi.org/10.5812/archcid.17580en
URIhttps://brieflands.com/journals/archcid/articles/20916en
KeywordMucormycosisen
KeywordOrbital Diseasesen
KeywordMiddle Cerebral Arteriesen
PublisherBrieflandsen
TitleA Case of Progressive Rhino-Orbital Mucormycosis Involving the Brain Via Direct Extension, Retrograde Perineural Spreading and Middle Cerebral Artery Vasculopathyen
TypeCase Reporten

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