Effects of aging on cholinergic and adrenergic systems responsiveness of rat isolated atrium

Abstract

Background : Aging is associated with changes in drugs responsiveness. Objective: To determine the effects of aging on cholinergic and adrenergic systems of rat isolated atrium. Methods:In this study isolated atrium of male albino rats were prepared. The rats were randomly selected & divided into 3 groups of 10-20 days (A), 2 months (B) & over 6 months old (C) (6