Whole Lung Lavage of Nine Children with Pulmonary Alveolar Proteinosis: Experience in a Tertiary Lung Center

AuthorBadiozaman Radpayen
AuthorTahereh Parsaen
AuthorShideh Dabiren
AuthorMohammadreza Boloursazen
AuthorAhmadreza Arbaben
AuthorSeyyedahmad Tabatabaeien
Issued Date2013-02-28en
AbstractBackground: Pulmonary alveolar proteinosis (PAP) is a rare disease in children, characterized by intra-alveolar accumulation of large amounts of surfactant proteins, which severely reduce gas exchange. Whole lung lavage (WLL) is the preferred technique for the treatment of severe PAP. Case Presentation: This report presents nine pediatric cases with advanced PAP who underwent WLL under general anesthesia during a 9 year period. One patient was treated with multiple unilateral WLL without employing cardiopulmonary bypass (CPB) and eight cases were treated by simultaneous lavage of both lungs using partial CPB. Conclusion: Our experience suggested that partial CPB was useful to support oxygenation during WLL in small children with severe PAP in whom lung separation and selective lavaging of each lung were impracticable.en
DOIhttps://doi.org/en
KeywordPulmonary Alveolar Proteinosisen
KeywordChildrenen
KeywordCardiopulmonary Bypassen
KeywordWhole Lung Lavageen
PublisherBrieflandsen
TitleWhole Lung Lavage of Nine Children with Pulmonary Alveolar Proteinosis: Experience in a Tertiary Lung Centeren
TypeCase Reporten

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