The protective effect of curcumin on scopolamine induced spatial learning and memory deficits in rats

Abstract

Background: The cholinergic system plays an important role in learning and memory. Administration of extracts of Curcuma longa or its constituent, curcumin, have some roles in cognitive function in animals. The aim of the present study was to investigate the effects of curcumin in preventing spatial performance impairment induced by scopolamine, a cholinergic receptor antagonist, in rats using Morris Water Maze (MWM).