Cast Bronchitis in a Cystic Fibrosis Child: Experience with Direct Instillation of Dornase Alfa as an Adjunct Treatment Agent
| Author | Sedigheh Yousefzadegan | en |
| Author | Rohollah Shirzadi | en |
| Author | Safura Navaie | en |
| Author | Alireza Takzare | en |
| Author | Mahdieh Ghaempanah | en |
| Author | Mohammadreza Modaresi | en |
| Orcid | Rohollah Shirzadi [0000-0002-5468-495X] | en |
| Orcid | Mohammadreza Modaresi [0000-0002-2132-9126] | en |
| Issued Date | 2019-10-31 | en |
| Abstract | Introduction: Lobar atelectasis is one of the common problems in patients with cystic fibrosis and can be a cause of respiratory symptoms in these patients even in the absence of bacterial infection. Case Presentation: Here we introduce a 9-year-old boy with cystic fibrosis who had many admissions because of respiratory distress due to lung collapse mainly caused by plastic bronchitis. Conclusions: In a number of patients with cystic fibrosis, lobar atelectasis is seen which is resistant to medical treatments. Early fiberoptic bronchoscopy as a measure for mechanical removal of the blocking agent and sometimes direct injection of drugs like dornase alfa into the bronchus is a successful modality in the treatment of lobar collapses in chronic pulmonary diseases. | en |
| DOI | https://doi.org/10.5812/ijp.89703 | en |
| Keyword | Cystic Fibrosis | en |
| Keyword | Atelectasis | en |
| Keyword | Plastic Bronchitis | en |
| Keyword | Fiberoptic Bronchoscopy | en |
| Keyword | Dornase Alfa | en |
| Keyword | N-Acetyl Cysteine | en |
| Publisher | Brieflands | en |
| Title | Cast Bronchitis in a Cystic Fibrosis Child: Experience with Direct Instillation of Dornase Alfa as an Adjunct Treatment Agent | en |
| Type | Case Report | en |