Cutaneous Polyarteritis Nodosa in Childhood: A Case Report
| Author | Şeyda Doğantan | en |
| Author | Sema Nur Taşkın | en |
| Author | Figen Cakmak | en |
| Author | Merve Karakoyun | en |
| Author | Harbiye Dilek Canat | en |
| Orcid | Şeyda Doğantan [0000-0002-9082-6804] | en |
| Orcid | Sema Nur Taşkın [0000-0003-3400-1514] | en |
| Orcid | Figen Cakmak [0000-0002-1667-2480] | en |
| Orcid | Merve Karakoyun [0009-0004-6302-4381] | en |
| Orcid | Harbiye Dilek Canat [0000-0003-1221-907X] | en |
| Issued Date | 2025-08-31 | en |
| Abstract | Introduction: Cutaneous polyarteritis nodosa (cPAN) is a rare form of pediatric vasculitis affecting small-to-medium-sized arteries at the dermo-subcutaneous junction and panniculus. It is essential to be aware of cPAN early to prevent misdiagnosis and guide the appropriate treatment. Case Presentation: A 5-year-old girl presented with relapsing rashes on the dorsum of the hands and feet, along with palpable, mobile, and non-indurated cervical lymphadenopathy on both sides of the neck. Skin biopsy revealed fibrinoid necrosis, orthokeratosis in the epidermis, a well-structured epithelium, perivascular sparse lymphocytes in the upper dermis, and neutrophil-rich inflammatory infiltrates in the medium-sized vessel walls of the subcutaneous fat tissue. The presence of medium-sized vasculitis in the skin biopsy confirmed cPAN. Conclusions: This case highlights the importance of cPAN in pediatric patients with cutaneous lesions. Although it is rare in childhood, given its chronic and recurrent nature, long-term follow-up is essential to monitor disease progression, assess treatment response, and prevent complications. | en |
| DOI | https://doi.org/10.5812/ijpediatr-157320 | en |
| URI | https://brieflands.com/journals/ijp/articles/157320 | en |
| Keyword | Vasculitis | en |
| Keyword | Cutaneous Vasculitis | en |
| Keyword | Cutaneous Polyarteritis Nodosa | en |
| Keyword | Biopsy | en |
| Publisher | Brieflands | en |
| Title | Cutaneous Polyarteritis Nodosa in Childhood: A Case Report | en |
| Type | Case Report | en |