Acute Lymphoblastic Leukemia in Two Patients with β-Thalassemia Major
| Author | Majid Naderi | en |
| Author | Ebrahim Miri Moghaddam | en |
| Author | Shaban Alizadeh | en |
| Author | Akbar Dorgalaleh | en |
| Author | Shadi Tabibian | en |
| Issued Date | 2014-11-28 | en |
| Abstract | Occurrence of leukemia in thalassemia major is a rare presentation. Here we report two cases of thalassemic patients, developing acute lymphoblastic leukemia. The genetic analysis revealed that, female and male patients were homozygous for IVSI-6 and IVSI-5, respectively. Two years ago the female patient presented by a high leukocyte count (154,000 µL) and male one also presented by 80,000 WBC/µL count 1 year ago. Microscopic examination of both patients revealed lymphoblasts that morphologically accommodate with ALL-L1 that were confirmed by photocytometry. | en |
| DOI | https://doi.org/ | en |
| Keyword | Thalassemia major | en |
| Keyword | Leukemia | en |
| Keyword | Transfusion | en |
| Publisher | Brieflands | en |
| Title | Acute Lymphoblastic Leukemia in Two Patients with β-Thalassemia Major | en |
| Type | Case Report | en |
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