Factor XIII Deficiency, Review of the Literature and Report of a Case

Abstract

Introduction: Factor XIII deficiency is a relatively rare hereditary bleeding disorder, which is usually found during infancy or early childhood. This condition may involve both genders within different races in an equal manner. Its incidence is estimated at approximately 1 in 106 live births. Patients with factor XIII deficiency are presented with a pattern of neonatal hemorrhage and lifelong bleeding diathesis. Case Presentation: A five-year-old female is presented here, who was diagnosed as a definite case of factor XIII deficiency, based on the clinical and laboratory findings at a medical specialist clinic. Typical clinical features of the disorder were the chief complaint of the patient, which was severe bleeding when she was brought into a specialized dental office following an earlier dental procedure. Conclusions: The case was fully investigated and diagnosed as a case with factor XIII deficiency causing such uncontrolled bleeding after extraction of a tooth.