Clinicopathology Figures and Survival of Non-Hodgkin’s Lymphoma in Iran
| Author | Safa Najafi | en |
| Author | Mehrdad Payandeh | en |
| Author | Masoud Sadeghi | en |
| Orcid | Mehrdad Payandeh [0000-0002-8941-1783] | en |
| Issued Date | 2017-01-31 | en |
| Abstract | Background: Non-Hodgkin’s lymphoma (NHL) is the fifth most frequently diagnosed cancer whose incidence has risen by at least 100 percent over the past five decades especially in the West. Objectives: The aim of this study is to investigate Clinicopathology figures, overall survival (OS) and Progression-free survival (PFS) in patients with NHL in Iran. Methods: In a descriptive study, 143 patients referred to Clinic of Hematology in two centers between 2005 and 2014. We checked age, sex, types and subtypes of NHL; recurrence, Ki-67, organomegaly, lymphadenopathy, radiotherapy, OS and PFS in the patients. The mean follow-up was 49 months. All patients received R-CHOP regimen for 6 to 8 cycles. Results: The mean age at diagnosis for the patients was 46 years (range, 16 - 82) and 76.9% had age < 60 years and 62.2% were male. 58% patients had primary nodal NHL and out of 139 patients, 88.5% were aggressive NHL. Organomegaly and lymphadenopathy were in 12 patients (8.4%) and 80 (55.9%), respectively. Of all patients, 106 patients (74.1%) were treated with radiotherapy. 2-year OS rate was 91.5% and 5-year OS rate was 85%.2-and 5-year PFS rates were 79.6% and 63.3%, respectively. Conclusions: Percentage of NHL in males is more than females and the median age is around 45 years. Also, the prevalence of nodal is more compared with extranodal in NHL patients. | en |
| DOI | https://doi.org/10.17795/ijcp-5226 | en |
| Keyword | Non-Hodgkin’s Lymphoma | en |
| Keyword | Overall Survival | en |
| Keyword | Progression-Free Survival | en |
| Keyword | Lymphadenopathy | en |
| Publisher | Brieflands | en |
| Title | Clinicopathology Figures and Survival of Non-Hodgkin’s Lymphoma in Iran | en |
| Type | Research Article | en |
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