The Efficacy and Safety of Fluoxetine Delayed-Release 90 mg/Weekly in Psychiatry: An Evidence-Based Mini-Review
| Author | Niayesh Mohebbi | en |
| Author | Mahtab Motamed | en |
| Author | Mahsa Panahishokouh | en |
| Orcid | Niayesh Mohebbi [0000-0002-1420-7286] | en |
| Orcid | Mahtab Motamed [0000-0002-8934-7865] | en |
| Orcid | Mahsa Panahishokouh [0000-0002-9648-2651] | en |
| Issued Date | 2024-09-30 | en |
| Abstract | Context: Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), is widely used in the treatment of various psychiatric disorders. While the standard therapeutic dose of fluoxetine is typically 20 - 60 mg per day, slow-release higher doses, such as 90 mg/weekly and more recently 180 mg/weekly, have been explored to assess their potential benefits in certain psychiatric conditions. This mini-review aims to evaluate the evidence regarding the effects, efficacy, and safety profile of fluoxetine at a dosage of 90 mg in psychiatry. Evidence Acquisition: A comprehensive literature search was conducted using electronic databases (PubMed and Embase) to identify relevant studies published until July 2023. Studies investigating the use of fluoxetine at a dosage of 90 mg/week in psychiatric conditions were included. The identified studies were critically appraised for their methodology and quality. Results: Limited research has specifically examined the effects of fluoxetine at a dosage of 90 mg/week in psychiatry. However, some studies have investigated this dosage form and provided insights into its potential efficacy in treating certain psychiatric conditions, such as major depressive disorder (MDD), obsessive-compulsive disorder (OCD), premature ejaculation, and premenstrual dysphoric disorder. These studies have shown that compliance with weekly fluoxetine was better than with once-daily dosing. Conclusions: Once-weekly dosing may be effective in psychiatry, improving compliance and enhancing psychological well-being. | en |
| DOI | https://doi.org/10.5812/ijpbs-146023 | en |
| URI | https://brieflands.com/journals/ijpbs/articles/146023 | en |
| Keyword | Efficacy | en |
| Keyword | Fluoxetine | en |
| Keyword | Once-Weekly | en |
| Keyword | Safety | en |
| Publisher | Brieflands | en |
| Title | The Efficacy and Safety of Fluoxetine Delayed-Release 90 mg/Weekly in Psychiatry: An Evidence-Based Mini-Review | en |
| Type | Review Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- ijpbs-18-3-146023-publish-pdf.pdf
- Size:
- 184.2 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF