Methoxylated Flavones from <i>Salvia Mirzayanii </i>Rech. f. and Esfand with Immunosuppressive Properties
Author | Abdul Majid Ayatollahi | en |
Author | Mustafa Ghanadian | en |
Author | Rahman Att-ur-Rahman | en |
Author | M. Ahmed Mesaik | en |
Author | Ahmad Shukralla Khalid | en |
Author | Fateme Adeli | en |
Issued Date | 2015-07-31 | en |
Abstract | Aerial parts of Salvia Mirzayanii was extracted with methanol. Methanol extract was suspended in water and defatted with petroleum ether. The defatted part was then partitioned between ethyl acetate and water. The ethyl acetate partition was chromatographed on a silica gel column to afford several fractions. Lymphocyte proliferation inhibitory assay of the resulted fractions was compared in-vitro and the fraction with more immunosuppressive activity was subjected to more purification to yield three methoxylated flavones: 5,7-dihydroxy,6,4’– dimethoxyflavone(1), 5-hydroxy,6,7,3’,4’–tetramethoxyflavone(2) and 5,3’-dihydroxy,6,7,4’– trimethoxyflavone (3). | en |
DOI | https://doi.org/10.22037/ijpr.2015.1696 | en |
Keyword | Methoxylated flavones | en |
Keyword | <i>Salvia Mirzayanii</i> | en |
Keyword | Immunosuppressive | en |
Keyword | Oxidative burst | en |
Keyword | T-cell proliferation | en |
Publisher | Brieflands | en |
Title | Methoxylated Flavones from <i>Salvia Mirzayanii </i>Rech. f. and Esfand with Immunosuppressive Properties | en |
Type | Original Article | en |
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