Methoxylated Flavones from <i>Salvia Mirzayanii </i>Rech. f. and Esfand with Immunosuppressive Properties

AuthorAbdul Majid Ayatollahien
AuthorMustafa Ghanadianen
AuthorRahman Att-ur-Rahmanen
AuthorM. Ahmed Mesaiken
AuthorAhmad Shukralla Khaliden
AuthorFateme Adelien
Issued Date2015-07-31en
AbstractAerial parts of Salvia Mirzayanii was extracted with methanol. Methanol extract was suspended in water and defatted with petroleum ether. The defatted part was then partitioned between ethyl acetate and water. The ethyl acetate partition was chromatographed on a silica gel column to afford several fractions. Lymphocyte proliferation inhibitory assay of the resulted fractions was compared in-vitro and the fraction with more immunosuppressive activity was subjected to more purification to yield three methoxylated flavones: 5,7-dihydroxy,6,4’– dimethoxyflavone(1), 5-hydroxy,6,7,3’,4’–tetramethoxyflavone(2) and 5,3’-dihydroxy,6,7,4’– trimethoxyflavone (3).en
DOIhttps://doi.org/10.22037/ijpr.2015.1696en
KeywordMethoxylated flavonesen
Keyword<i>Salvia Mirzayanii</i>en
KeywordImmunosuppressiveen
KeywordOxidative bursten
KeywordT-cell proliferationen
PublisherBrieflandsen
TitleMethoxylated Flavones from <i>Salvia Mirzayanii </i>Rech. f. and Esfand with Immunosuppressive Propertiesen
TypeOriginal Articleen

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