The Role of LncRNA ROR in Colorectal Cancer Diagnosis and Treatment

AuthorSeyed Mostafa Ghasemi Najarkolaeeen
AuthorMohammad Kordkatoulien
AuthorZahra Salarien
AuthorReza Yusofvanden
AuthorPooya Samianen
OrcidMohammad Kordkatouli [0009-0006-3008-6820]en
OrcidZahra Salari [0009-0007-6232-0703]en
OrcidReza Yusofvand [0009-0001-2287-9912]en
OrcidPooya Samian [0009-0004-8546-0336]en
Issued Date2025-01-31en
AbstractContext: Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths worldwide, particularly in developed countries. Despite advances in detection and treatment, CRC remains difficult to diagnose in its early stages, complicating patient outcomes. Recently, long non-coding RNAs (lncRNAs) have emerged as significant regulators in cancer biology, offering new opportunities for cancer diagnostics. Evidence Acquisition: This review highlights the molecular mechanisms through which LncRNA ROR influences CRC development, its diagnostic potential as a biomarker, and the future challenges of integrating LncRNA ROR into clinical practice. Results: Future research must focus on large-scale validation studies and explore the therapeutic implications of targeting LncRNA ROR. Conclusions: Overall, this review positions LncRNA ROR as a promising biomarker with potential applications in both CRC diagnosis and treatment.en
DOIhttps://doi.org/10.5812/zjrms-158156en
KeywordColorectal Cancer (CRC)en
KeywordLong Non-coding RNAs (lncRNAs)en
KeywordLncRNA RORen
KeywordBiomarkersen
PublisherBrieflandsen
TitleThe Role of LncRNA ROR in Colorectal Cancer Diagnosis and Treatmenten
TypeReview Articleen

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