The Role of LncRNA ROR in Colorectal Cancer Diagnosis and Treatment
Author | Seyed Mostafa Ghasemi Najarkolaee | en |
Author | Mohammad Kordkatouli | en |
Author | Zahra Salari | en |
Author | Reza Yusofvand | en |
Author | Pooya Samian | en |
Orcid | Mohammad Kordkatouli [0009-0006-3008-6820] | en |
Orcid | Zahra Salari [0009-0007-6232-0703] | en |
Orcid | Reza Yusofvand [0009-0001-2287-9912] | en |
Orcid | Pooya Samian [0009-0004-8546-0336] | en |
Issued Date | 2025-01-31 | en |
Abstract | Context: Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths worldwide, particularly in developed countries. Despite advances in detection and treatment, CRC remains difficult to diagnose in its early stages, complicating patient outcomes. Recently, long non-coding RNAs (lncRNAs) have emerged as significant regulators in cancer biology, offering new opportunities for cancer diagnostics. Evidence Acquisition: This review highlights the molecular mechanisms through which LncRNA ROR influences CRC development, its diagnostic potential as a biomarker, and the future challenges of integrating LncRNA ROR into clinical practice. Results: Future research must focus on large-scale validation studies and explore the therapeutic implications of targeting LncRNA ROR. Conclusions: Overall, this review positions LncRNA ROR as a promising biomarker with potential applications in both CRC diagnosis and treatment. | en |
DOI | https://doi.org/10.5812/zjrms-158156 | en |
Keyword | Colorectal Cancer (CRC) | en |
Keyword | Long Non-coding RNAs (lncRNAs) | en |
Keyword | LncRNA ROR | en |
Keyword | Biomarkers | en |
Publisher | Brieflands | en |
Title | The Role of LncRNA ROR in Colorectal Cancer Diagnosis and Treatment | en |
Type | Review Article | en |
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