Risk Factors for Severe Outcomes in Bacterial Meningitis
| Author | Daniela Caldas Teixeira | en |
| Author | Lilian Martins Oliveira Diniz | en |
| Author | Henrique Moravia de Andrade Santos Moreira | en |
| Author | Marcelle Marie Martins Maia | en |
| Author | Leonardo Hosken Dornellas | en |
| Author | Maria Luiza Custodio Soares | en |
| Author | Roberta Maia de Castro Romanelli | en |
| Orcid | Daniela Caldas Teixeira [0000-0001-7899-2212] | en |
| Orcid | Lilian Martins Oliveira Diniz [0000-0001-7802-4377] | en |
| Orcid | Henrique Moravia de Andrade Santos Moreira [0000-0002-5340-5955] | en |
| Orcid | Marcelle Marie Martins Maia [0000-0001-8791-4320] | en |
| Orcid | Leonardo Hosken Dornellas [0000-0001-5361-2148] | en |
| Orcid | Maria Luiza Custodio Soares [0000-0001-5164-5739] | en |
| Orcid | Roberta Maia de Castro Romanelli [0000-0002-1660-0751] | en |
| Issued Date | 2021-12-31 | en |
| Abstract | Objectives: This study aimed to define risk factors associated with suppurative complications, short-term sequelae, and death in pediatric patients with bacterial meningitis. Methods: A retrospective cohort study was conducted on children with bacterial meningitis, aged 0 months to 18 years, who were admitted to the Hospital Infantil João Paulo II, reference in infectious diseases, from 2005 to 2018. Results: In 178 cases, meningococcal meningitis was the most prevalent disease form (51%), followed by pneumococcal meningitis (31%) and Haemophilus influenzae type B meningitis (10%). The main clinical findings at admission were fever (93.1%), vomiting (67.9%), drowsiness (47.8%), headache (36.5%), irritability (28.3%), and seizures (26.4%). Suppurative complications were recorded in 19% of the patients. The prevalence of neurological sequelae during hospital discharge was 12.4%. Hearing (41%; n = 9) and cognitive (9%) impairments were prominent among the diagnosed sequelae. Incidences of epileptic crises, vestibular disorders, or hydrocephalus were noted in one case each (4.5%), and 12.4% of the patients died. Conclusions: Streptococcus pneumoniae and H. influenzae type B were associated with the diagnosis of sequelae during hospital discharge, seizures were considered a risk factor for suppurative complications, and gastrointestinal symptoms or signs of clinical severity were associated with death. | en |
| DOI | https://doi.org/10.5812/archcid-110134 | en |
| Keyword | Bacterial Meningitis | en |
| Keyword | Pediatrics | en |
| Keyword | Infectious Complications | en |
| Keyword | Death | en |
| Publisher | Brieflands | en |
| Title | Risk Factors for Severe Outcomes in Bacterial Meningitis | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- archcid-16-6-110134.pdf
- Size:
- 897.46 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF