Experimental and Clinical Evaluation of Plantago australis Extract as an Anti-Inflammatory Agent to Treat Oral Pathologies
| Author | Isadora Luana Flores | en |
| Author | Thiago de Oliveira Gamba | en |
| Author | Rodrigo Varella de Carvalho | en |
| Author | Rafael Guerra Lund | en |
| Author | Adriana Etges | en |
| Issued Date | 2016-10-01 | en |
| Abstract | Background: Plantago australis is a native plant from Southern Brazil used to reduce inflammation. Interestingly, there are no previous studies evaluating its use to treat oral lesions. Objectives: The study aimed to investigate in vivo the anti-inflammatory activity of 10% ethanol extract of P. australis in recurrent aphthous stomatitis (RAS), erosive lichen planus (ELP) and actinic cheilitis (AC). Methods: Thirty patients with RAS, ELP and AC were treated topically with 10% P. australis solution-based or cream. Results: In the comparison of in vivo data before and after the treatment and between different lesions, all P values were less than 0.05. Conclusions: The pharmaceutical formulation of 10% P. australis was therapeutically effective in the subjects with inflammatory oral lesions of RAS, ELP and AC. | en |
| DOI | https://doi.org/10.17795/jjhr-39105 | en |
| Keyword | <i>Plantago</i> spp. | en |
| Keyword | Anti-Inflammatory Agents | en |
| Keyword | Oral Pathology | en |
| Keyword | Clinical Study | en |
| Publisher | Brieflands | en |
| Title | Experimental and Clinical Evaluation of Plantago australis Extract as an Anti-Inflammatory Agent to Treat Oral Pathologies | en |
| Type | Research Article | en |
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