The Relationship Between Early Weight Z-Score Changes and Nutritional Differences in Very Low Birth Weight Infants During Hospital Stay
Author | Chu-yi Guo | en |
Author | Mu-xue Yu | en |
Author | Lin-xia Deng | en |
Author | Wang-kai Liu | en |
Author | Si-qi Zhuang | en |
Issued Date | 2018-08-31 | en |
Abstract | Background: Advances in neonatal care have resulted in improved survival for very low birth weight infants (VLBWIs). However, the main factors that lead to early weight Z-score [standard deviation score (SDS)] changes during hospital stay in VLBWIs still need to be studied more. Objectives: In this study we aimed to investigate the differences in specific factors that relate to VLBWIs’ early weight Z-score changes as the scientific basis for clinical practice of VLBWIs during the entire hospital stay. Methods: We retrospectively reviewed baseline characteristics, nutrition management, clinical outcomes, and complications between non-catch-down (NCD) (Δ weight SDS ≥ -0.67) and catch-down (CD) groups (Δ weight SDS < -0.67) in VLBWIs during hospital stay. Results: A total of 227 infants (NCD group = 117, CD group = 110) met the inclusion criteria. No significant differences were found in baseline characteristics between the two groups. The NCD group received higher parenteral lipids (g/kg/d) from day 5 to day 7 and higher enteral feeding volume (mL/kg/d) from day 5 to week 5. The NCD group had higher protein:energy ratios at day 2 to day 4 and day 7 and higher total energy (kcal/kg/d) during the first six weeks. The NCD group had lower incidence of bronchopulmonary dysplasia (BPD) and parenteral nutrition-associated cholestasis (PNAC). Conclusions: This study showed that adequate parenteral lipid and energy at the first week of life and earlier enhanced enteral feeding volume might significantly improve the VLBWIs’ weight Z-scores during hospital stay. The VLBWIs with catch-down growth might be more prone to developing BPD and PNAC. | en |
DOI | https://doi.org/10.5812/ijp.62520 | en |
Keyword | Parenteral Nutrition | en |
Keyword | Enteral Nutrition | en |
Keyword | Very Low Birth Weight Infant | en |
Publisher | Brieflands | en |
Title | The Relationship Between Early Weight Z-Score Changes and Nutritional Differences in Very Low Birth Weight Infants During Hospital Stay | en |
Type | Research Article | en |
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